Visceral Adiposity Index and Lipid Accumulation Product Related to Insulin Resistance and Metabolic Syndrome in Obese College Students

Fillah Fithra Dieny; A. Fahmy Arif Tsani; Suryawati Suryawati

doi:10.3889/oamjms.2022.8880

Authors

Fillah Fithra Dieny Departemen of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia https://orcid.org/0000-0001-6071-8901
A. Fahmy Arif Tsani Departemen of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia; Center of Nutrition Research, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia
Suryawati Suryawati Departemen of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.8880

Keywords:

Adolescent girls, Insulin resistance, Metabolic syndrome, Obesity, Visceral adiposity index

Abstract

BACKGROUND: Visceral obesity in adolescent girls increased the risk of cardiometabolic disease. A simple indicator has been developed to assess metabolic risk through visceral adiposity index (VAI) and lipid accumulation product (LAP) in people with visceral obesity.

AIM: This study analyzed the relationship between VAI and LAP with insulin resistance (IR) and metabolic syndrome (MS) in obese female adolescents.

METHODS: An observational study was conducted on 120 students at Universitas Diponegoro. VAI was obtained from calculation formulations which includes body mass index, waist circumference (WC), triglycerides (TGs), and High-density lipoprotein (HDL) cholesterol. LAP was obtained from calculation formulation which include WC and TGs. IR values were obtained based on the calculation of homeostasis for assessment models IR. The metabolic syndrome score (cMetS) was obtained by the calculation of components of WC, blood pressure, fasting blood glucose, TG, and HDL cholesterol. Bivariate analysis using the Spearman Rank correlation test.

RESULTS: We found that 40% of subjects had a VAI score that was considered at risk. As many as 20.8% of obese adolescent girls experience MetS while the other 79.2% are pre-metabolic syndrome and 83.3% of subjects have experienced IR. VAI showed a significant relationship with IR (p ≤ 0.001; r = 0.667) and cMetS (p = 0.007; p = 0.245). LAP showed a significant relationship with IR (p < 0,001; r = 0,385) and MS (p < 0,001; r = 0.372).

CONCLUSION: We found that VAI and LAP could be an indicator for estimating IR and MS in obese female adolescent.

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