Ten Percent Red Ginger Gel Relieves Knee Joint Pain on the Elderly with Osteoarthritis

Authors

  • Rusmini Rusmini Department of Nursing, Mataram Health Polytechnic Ministry of Health, Mataram, Indonesia
  • Mira Utami Ningsih Department of Nursing, Mataram Health Polytechnic Ministry of Health, Mataram, Indonesia
  • Desty Emilyani Department of Nursing, Mataram Health Polytechnic Ministry of Health, Mataram, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.8891

Keywords:

Complementary therapy, Elderly, Joint pain, Osteoarthritis, Red ginger

Abstract

BACKGROUND: Osteoarthritis is a disease that causes inflammation, injury, and loss of structure and function of cartilages. A nonpharmacological treatment that is considered to be effective and safe and has minimal side effects is red ginger.

AIM: This study investigates the chemical constituents of red ginger extract and the effectiveness of red ginger gel in reducing knee joint pain in the elderly with osteoarthritis.

METHODS: This research is a quasi-experimental study with pre- and post-test design. Samples were selected using a purposive sampling technique. The intensity of knee joint pain pre- and postadministration of 0% (control group) and 10% (intervention group) red ginger gel and the chemical components of red ginger extract were collected. Gas chromatography–mass spectrometry analysis showed four different components of essential oils that have anti-inflammatory and analgesic effects in the red ginger extract.

RESULTS: Results showed no difference in the pre- and post-test result in the control group (p = 0.16 > 0.05). Significant differences were found in the pre- and post-test results of the intervention group (p = 0.001 < 0.05). There was a significant difference in the decrease of knee joint pain after intervention between the two groups (p = 0.001 < 0.05).

CONCLUSION: It can be concluded that 10% red ginger gel is effective in reducing knee joint pain in the elderly with osteoarthritis.

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References

Arayanti PI, Haryanto J, Ulfiana E. Red ginger (Zingiber officinale var. rubrum) massage reduces stiffness and functional disability in elderly with osteoarthritis. J Ners. 2018;13(2):200-6. https://doi.org/10.20473/jn.v13i2.9292 DOI: https://doi.org/10.20473/jn.v13i2.9292

Wittenauer R, Smith L, Aden K. Background Paper 6.12 Osteoarthritis. Geneva: World Health Organisation; 2013.

Herman S. In: Bahasa Indonesia, Puspasari N, editor. Basic Health Research on Joint Disease. Jakarta: Lembaga Penerbitan Badan Litbangkes; 2014.

Grässel S, Muschter D. Recent advances in the treatment of osteoarthritis. F1000Res 2020;9:F1000 Faculty Rev-325. https://doi.org/10.12688/f1000research.22115.1 DOI: https://doi.org/10.12688/f1000research.22115.1

Wittenauer R, Smith L, Aden K. Priority Medicines for Europe and the World “A Public Health Approach to Innovation” Background Paper 6.12. Osteoarthritis; 2013.

Tejawati U, Erwin E, Utami GT. Comparison of the effectiveness of lemongrass compress and elephant ginger compress against joint pain in the elderly (In Bahasa Indonesia). J Online Mahasiswa. 2018;5(2):770-6.

Yusuf E. Pharmacologic and non-pharmacologic treatment of osteoarthritis. Curr Treatment Options Rheumatol. 2016;2(2):111-25. https://doi.org/10.1007/s40674-016-0042-y DOI: https://doi.org/10.1007/s40674-016-0042-y

Pawanti S, Untari EK, Nansy E. Identification of osteoarthritis drugs and costs in geriatric patients at the outpatient installation of sultan Syarif Mohamad Alkadrie hospital, Pontianak City. Tanjungpura University, Pontianak. (In Bahasa Indonesia). J Mahasiswa Farm Fakult Kedokteran UNTAN. 2015. https://doi.org/10.36387/jiis.v6i2.640 DOI: https://doi.org/10.36387/jiis.v6i2.640

Kaban AN, Tarigan D, Saleh C. Uji fitokimia, toksisitas dan aktivitas antioksidan fraksi n-heksan dan etil asetat terhadap ekstrak jahe merah (Zingiber officinale var. amarum). J Kimia Mulawarman. 2016;14(1):24-28. https://doi.org/10.26874/jkk.v2i1.23 DOI: https://doi.org/10.26874/jkk.v2i1.23

Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, et al. Anti-inflammatory properties of red ginger (Zingiber officinale var. rubra) extract and suppression of nitric oxide production by its constituents. J Med Food. 2010;13(1):156-62. https://doi.org/10.1089/jmf.2009.1084 PMid:20136450 DOI: https://doi.org/10.1089/jmf.2009.1084

Unuofin JO, Masuku NP, Paimo OK, Lebelo SL. Ginger from farmyard to town: Nutritional and pharmacological applications. Front Pharmacol. 2021;12:779352. https://doi.org/10.3389/fphar.2021.779352 PMid:34899343 DOI: https://doi.org/10.3389/fphar.2021.779352

Srinivasan K. Ginger rhizomes (Zingiber officinale): A spice with multiple health beneficial potentials. Pharm Nutr. 2017;5(1):18-28. https://doi.org/10.1016/j.phanu.2017.01.001 DOI: https://doi.org/10.1016/j.phanu.2017.01.001

Bartels EM, Folmer VN, Bliddal H, Altman RD, Juhl C, Tarp S, et al. Efficacy and safety of ginger in osteoarthritis patients: A meta-analysis of randomized placebo-controlled trials. Osteoarthritis Cartilage. 2015;23(1):13-21. https://doi.org/10.1016/j.joca.2014.09.024 PMid:25300574 DOI: https://doi.org/10.1016/j.joca.2014.09.024

Muhlisah. Family Medicinal Plants (In Bahasa Indonesia). Jakarta: Swadaya; 2011.

Rahayu HT, Sri N, Sunardi S. The effectiveness of red ginger compress therapy (Zingiber officinale rosc. var. rubrum) on elders with joint pain. Adv Health Sci Res. 2017;2:374-80. https://doi.org/10.2991/hsic-17.2017.58 DOI: https://doi.org/10.2991/hsic-17.2017.58

Baliga MS, Latheef L, Haniadka R, Fazal F, Mane PP, Kalekhan F, et al. Ginger (Zingiber officinale Roscoe) in the treatment of osteoarthritis: Clinical observations and mechanistic insights. In: Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Amsterdam, Netherlands: Elsevier; 2015. p. 111-7. https://doi.org/10.1016/b978-0-12-418680-4.00012-9 DOI: https://doi.org/10.1016/B978-0-12-418680-4.00012-9

Farizal J, Mulyati L, Susiwati S. Kompres Jahe Merah Berpengaruh Terhadap Penurunan Skala Nyeri Osteoartritis Pada Lanjut Usia di Wilayah Kerja Puskesmas Kampung Delima Tahun 2016; 2016. https://doi.org/10.32668/jitek.v5i2.27

Masyhurrosyidi H, Kumboyono, Utami YW. The effect of hot compress decoction of ginger on subacute and chronic pain levels in the elderly with knee osteoarthritis at Arjuna Health Center, Klojen Subdistrict, Malang, East Java (In Bahasa Indonesia). Majalah Kesehatan Fakult Kedokteran. 2014;1(1):39-44.

Farizal J, Mulyati L, Susiwati S. Red ginger compress effect on reduction in osteoarthritis pain scale in the elderly in the work area of kampung delima health center in 2016 (In Bahasa Indonesia). J Ilmu Teknol Kesehatan. 2018;5(2):192-200. https://doi.org/10.32668/jitek.v5i2.27 DOI: https://doi.org/10.32668/jitek.v5i2.27

Indonesia PR. Diagnosis dan Penatalaksanaan Osteoartritis. Jakarta: Indonesia Rheumatology Association; 2014.

Ferraz MB, Quaresma M, Aquino L, Atra E, Tugwell P, Goldsmith C. Reliability of pain scales in the assessment of literate and illiterate patients with rheumatoid arthritis. J Rheumatol. 1990;17(8):1022-4. PMid:2213777

Palazzo C, Nguyen C, Lefevre-Colau MM, Rannou F, Poiraudeau S. Risk factors and burden of osteoarthritis. Ann Phys Rehabil Med. 2016;59(3):134-8. https://doi.org/10.1016/j.rehab.2016.01.006 PMid:26904959 DOI: https://doi.org/10.1016/j.rehab.2016.01.006

Prieto-Alhambra D, Judge A, Javaid MK, Cooper C, Diez- Perez A, Arden NK. Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: Influences of age, gender and osteoarthritis affecting other joints. Ann Rheum Dis. 2014;73(9):1659-64. https://doi.org/10.1136/annrheumdis-2013-203355 PMid:23744977 DOI: https://doi.org/10.1136/annrheumdis-2013-203355

Sudoyo. Ilmu Penyakit Dalam. Jakarta: Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia; 2006. https://doi.org/10.15395/mkb.v47n4.623 DOI: https://doi.org/10.15395/mkb.v47n4.623

Johnson VL, Hunter DJ. The epidemiology of osteoarthritis. Best Pract Res Clin Rheumatol. 2014;28(1):5-15. https://doi.org/10.1016/j.berh.2014.01.004 PMid:24792942 DOI: https://doi.org/10.1016/j.berh.2014.01.004

Dahlhamer J, Lucas J, Zelaya C, Nahin R, Mackey S, DeBar L, et al. Prevalence of chronic pain and high-impact chronic pain among adults United States, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(36):1001-6. https://doi.org/10.15585/mmwr.mm6736a2 PMid:30212442 DOI: https://doi.org/10.15585/mmwr.mm6736a2

Setyawan RA, Tasminatun S. The effectiveness of Zingiber officinale Linn var. rubrum extract cream in reducing joint pain in the elderly (In Bahasa Indonesia). Mutiara Med. 2016;13(2):105-10.

Ding M, Leach MJ, Bradley H. A systematic review of the evidence for topical use of ginger. Explore. 2013;9(6):361-4. https://doi.org/10.1016/j.explore.2013.08.001 PMid:24199775 DOI: https://doi.org/10.1016/j.explore.2013.08.001

Tjay TH, Raharja K. Obat-obat Penting, Khasiat, Penggunaan, dan Efek-Efek Sampingnya. 6th ed. Jakarta: Elex Media Komputindo; 2007. https://doi.org/10.24198/farmasetika.v2i5.16780 DOI: https://doi.org/10.24198/farmasetika.v2i5.16780

Hermayudi. Penyakit Rematik. Yogyakarta: Nuha Medika; 2017.

Ratna TS. Uji Efek Antiinflamasi Dari Kombinasi Ekstrak Rimpang Jahe Merah (Zingiber officinale Rosc.) dan Ekstrak Rimpang Kunyit (Curcuma domestica Val.) dalam Sediaan Topikal pada Mencit Jantan [Skripsi]. Sumatera Utara: Universitas Sumatera Utara; 2009. https://doi.org/10.36656/jpfh.v2i2.208 DOI: https://doi.org/10.36656/jpfh.v2i2.208

Minghetti P, Sosa S, Cilurzo F, Casiraghi A, Alberti E, Tubaro A, et al. Evaluation of the topical anti-inflammatory activity of ginger dry extracts from solutions and plasters. Plant Med. 2007;73(15):1525-30. https://doi.org/10.1055/s-2007-993741 PMid:18058610 DOI: https://doi.org/10.1055/s-2007-993741

Therkleson T. Topical ginger treatment with a compress or patch for osteoarthritis symptoms. J Holist Nurs. 2014;32(3):173-82. https://doi.org/10.1177/0898010113512182 PMid:24305660 DOI: https://doi.org/10.1177/0898010113512182

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Published

2022-04-14

How to Cite

1.
Rusmini R, Ningsih MU, Emilyani D. Ten Percent Red Ginger Gel Relieves Knee Joint Pain on the Elderly with Osteoarthritis. Open Access Maced J Med Sci [Internet]. 2022 Apr. 14 [cited 2024 Apr. 26];10(B):1164-9. Available from: https://oamjms.eu/index.php/mjms/article/view/8891