A-DROP Scoring System in Predicting Mortality within 30 Days of Hospitalization in Community-acquired Pneumonia Patients at H. Adam Malik General Hospital Medan
Keywords:A-DROP, 30-d mortality, Community-acquired pneumonia
BACKGROUND: Community-acquired pneumonia (CAP) is the leading cause of death among infectious diseases, contributing significantly to patient morbidity and mortality. Therefore, an accurate initial assessment of CAP severity should be performed immediately to determine the prognosis before starting the management. A-DROP scoring system is one of the initial assessments.
AIM: This study aimed to determine the accuracy of the A-DROP scoring system in predicting mortality within 30 days of hospitalization at H. Adam Malik General Hospital Medan.
METHODS: This is an observational study with a retrospective and cohort study. Data were obtained from the medical records of 76 CAP patients hospitalized from January 2018 to December 2018. Each patient was assessed with an A-DROP scoring system and the presence or absence of mortality within 30 days of hospitalization. The data were processed using statistical analysis to calculate the area under curve (AUC) on the receiver operating characteristic (ROC) curve. The optimal cutoff point is also analyzed using the Youden index.
RESULT: The ROC curve analysis showed that the AUC was 0.772 (95% CI: 0.666–0.978, p < 0.001). The accuracy of A-DROP scoring system is good (AUC:0.7−0.8). The optimal of the Youden index is 0.428 at the cutoff point A-DROP score >1.5, so that the optimal cutoff point is A-DROP score ≥2.CONCLUSION: The A-DROP scoring system has good accuracy in predicting mortality within 30 days of hospitalized CAP patients. The A-DROP scoring system has an accuracy similar to the PSI (Pneumonia Severity Index) and the CURB-65 scoring system.
Plum Analytics Artifact Widget Block
Ticona JH, Zaccone VM, McFarlane IM. Community-acquired pneumonia: A focused review. Am J Med Case Rep. 2021;9(1):45-52. https://doi.org/10.12691/ajmcr-9-1-12 PMid:33313398
Ferreira-Coimbra J, Sarda C, Rello J. Burden of community-acquired pneumonia and unmet clinical needs. Adv Ther. 2020;37(4):1302-18. https://doi.org/10.1007/s12325-020-01248-7 PMid:32072494
Regunath H, Oba Y. Community-Acquired Pneumonia. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430749 [Last accessed on 2020 Aug 10].
RESPIROLOGY ISO. Pneumonia Komunitas. 2nd ed. Jakarta: Badan Penerbit FK UI; 2014.
Kandi S. Diagnosis of Community Acquired Pneumonia. Suppl JAPI. 2012;60:17-19.
Ahn JH, Choi EY. Expanded A-DROP score: A new scoring system for the prediction of mortality in hospitalized patients with community-acquired pneumonia. Sci Rep. 2018;8(1):14588. https://doi.org/10.1038/s41598-018-32750-2
Liu J, Xu F, Zhou H, Wu X, Shi L, Lu R, et al. Expanded CURB- 65: A new score system predicts severity of community-acquired pneumonia with superior efficiency. Sci Rep. 2016;6(1):22911. PMid:26987602
Yuichiro S, Sato S, Maruyama E, Ohashi T, Ogawa M, Imaizumi K, et al. Comparison of severity scoring systems A-DROP and CURB-65 for community-acquired pneumonia. Respirology. 2008;13:731-5. https://doi.org/10.1111/j.1440-1843.2008.01329.x PMid:18713094
Nagai K, Horita N, Sato T, Yamamoto M, Nagakura H, Kaneko T. Age, dehydration, respiratory failure, orientation disturbance, and blood pressure score predicts in-hospital mortality in HIV-negative non-multidrug-resistant smear-positive pulmonary tuberculosis in Japan. Sci Rep. 2016;6:21610. https://doi.org/10.1038/srep21610 PMid:26883886
Simundic AM. Measures of diagnostic accuracy: Basic definitions. EJIFCC. 2009;19(4):203-11. PMid:27683318
Shehata SM, Sileem AE, Shahien NE. Prognostic values of pneumonia severity index, CURB-65 and expanded CURB-65 scores in community-acquired pneumonia in Zagazig University Hospitals. Egypt J Chest Dis Tuberc. 2017;66(3):549-55. https://doi.org/10.1016/j.ejcdt.2017.01.001
Nagano H, Takada D, Shin J-H, Morishita T, Kunisawa S, Imanaka Y. Hospitalization of mild cases of community-acquired pneumonia decreased more than severe cases during the COVID-19 pandemic. Int J Infect Dis. 2021;106:323-8. https://doi.org/10.1016/j.ijid.2021.05.026 PMid:33794382
Shindo Y, Sato S, Maruyama E, Ohashi T, Ogawa M, Imaizumi K, et al. Comparison of severity scoring systems A-DROP and CURB-65 for community-acquired pneumonia. Respirology. 2008;13(5):731-5. https://doi.org/10.1111/j.1440-1843.2008.01329.x PMid:18713094
BPS. Badan Pusat Statistik; 2015. Available from: https://www.bps.go.id/statictable/2014/09/22/1517/angka-harapan-hidup-penduduk-beberapa-negara-tahun-1995-2015.html [Last accessed on 2020 Dec 12].
Teixeira-Lopes F, Cysneiros A, Dias A, Durão V, Costa C, Paula F, et al. Intra-hospital mortality for community-acquired pneumonia in mainland Portugal between 2000 and 2009. Pulmonology. 2019;25(2):66-70. https://doi.org/10.1016/j.pulmoe.2018.06.004 PMid:30026065
Zhang ZX, Zhang W, Liu P, Yang Y, Tan WC, Ng HS, et al. Prognostic value of pneumonia severity index, CURB-65, CRB-65, and procalcitonin in community-acquired pneumonia in Singapore. Proc Singapore Healthc. 2015;25(3):139-47. https://doi.org/10.1177/2010105815623292
How to Cite
Copyright (c) 2022 Fransisco Sentosa Pakpahan, Syamsul Bihar, Fajrinur Syarani, Putri Eyanoer (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All rights reserved.