Speckle-tracking Echocardiography in Early Diagnosis of Myocardial Dysfunctions of Women with Hypertension in the Perimenopausal Period

Authors

  • Zhanar Balmukhamedova Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana Medical University”, Astana, Kazakhstan https://orcid.org/0000-0003-2626-0591
  • Gulmira Derbissalina Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana Medical University”, Astana, Kazakhstan https://orcid.org/0000-0003-3704-5061
  • Natalya Zemlyanskaya Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana Medical University”, Astana, Kazakhstan https://orcid.org/0000-0003-1968-3246
  • Aliya Dzholdasbekova Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana Medical University”, Astana, Kazakhstan
  • Dariga Blyalova Department of General Medical Practice with a Course of Evidence-Based Medicine, NJSC “Astana Medical University”, Astana, Kazakhstan

DOI:

https://doi.org/10.3889/oamjms.2022.9027

Keywords:

Speckle-tracking echocardiography, Arterial hypertension, Perimenopause

Abstract

Абстрактный

 

Цель исследования:  оценить роль спекл-трекинговой эхокардиографии в выявлении ранней дисфункции миокарда у женщин с артериальной гипертензией в перименопаузальном периоде.

 

Материал и методы. В исследовании приняли участие 50 женщин перименопаузального периода в возрасте от 45 до 55 лет. Перименопауза диагностировалась на основании клинического осмотра, включающего осмотр у гинеколога и исследования гормонального статуса женщины. Выборка женщин была разделена на две группы в зависимости от наличия артериальной гипертензии. В основную группу вошли 24 пациентки с артериальной гипертензией, диагностированной в перименопаузальном периоде. Перечисленные выше методы обследования также включали электрокардиографию, эхокардиографию и спекл-трекинговую эхокардиографию.

 

Результаты. По данным спекл-трекинговой эхокардиографии выявлены статистически значимые показатели в базально-антеропостероидном и нижнебазальном сегментах (р = 0,016; 0,001). Разница индекса массы миокарда левого желудочка была статистически значимой в сравниваемых группах (р = 0,038). ROC-анализ использовался для оценки качества полученной модели логистической регрессии. Площадь под ROC-кривой составила 0,806 ± 0,065 (95% ДИ: 0,679–0,933, p <0,001). Это указывает на «очень хорошее» прогностическое качество модели.

 

Заключение: в группе больных с артериальной гипертензией более чувствительны показатели базального переднеперегородочного и базально-нижнего сегментов, что может быть использовано как значимый показатель дисфункции при неизменных показателях стандартной эхокардиографии.

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Published

2022-04-15

How to Cite

1.
Balmukhamedova Z, Derbissalina G, Zemlyanskaya N, Dzholdasbekova A, Blyalova D. Speckle-tracking Echocardiography in Early Diagnosis of Myocardial Dysfunctions of Women with Hypertension in the Perimenopausal Period. Open Access Maced J Med Sci [Internet]. 2022 Apr. 15 [cited 2026 Oct. 22];10(B):1176-82. Available from: https://oamjms.eu/index.php/mjms/article/view/9027