Systolic Blood Pressure, Blood Glucose, and Mortality of Patients with Acute Coronary Syndrome
DOI:
https://doi.org/10.3889/oamjms.2022.9110Keywords:
Acute coronary syndrome, Blood glucose, Mortality, Systolic blood pressureAbstract
BACKGROUND: Acute coronary syndrome (ACS) is a cardiovascular disease causing a high number of patient mortality in the world as well as Indonesia. Systolic blood pressure (SBP) and blood glucose (BG) are suspected to be important indicators for determining the risk stratification and prognostic information of ACS.
AIM: This study aims to evaluate blood pressure and BG alongside the mortality of patients with ACS.
METHODS: This was a quantitative study conducted using a retrospective survey method and the secondary data used were obtained from the medical records in Dr. Iskak Hospital between January and December 2020. The study sample consists of 110 respondents selected with a proportionate stratified random sampling. Meanwhile, the independent variables were SBP (X1) and BG (X2) while the dependent variable was mortality in ACS patients (Y).
RESULTS: The multivariate analyses results with logistic regression show that SBP is associated with mortality with p = 0.008 and an odds ratio of 0.673. Furthermore, the BG was slightly higher in the multivariate model which has an odds ratio of 3.052 and was associated with mortality having p = 0.000.
CONCLUSION: Based on the result, a low SBP and high BG lead to ACS patient mortality, consequently, serious attention is needed on the SBP and blood sugar.
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Kemenkes RI. Laporan Nasional. Badan Penelitian dan Pengembangan Kesehatan; 2018.
Benamer S, Eljazwi I, Mohamed R, Masoud H, Tuwati M, Elbarsha AM. Association of hyperglycemia with in-hospital mortality and morbidity in Libyan patients with diabetes and acute coronary syndromes. Oman Med. J. 2015;30(5):326-30. https://doi.org/10.5001/omj.2015.67 PMid:26421112 DOI: https://doi.org/10.5001/omj.2015.67
Smith JN, Negrelli JM, Manek MB, Hawes EM, Viera AJ. Diagnosis and management of acute coronary syndrome : An evidence-based update. J Am Board Fam Med. 2015;28(2):283-93. https://doi.org/10.3122/jabfm.2015.02.140189 PMid:25748771 DOI: https://doi.org/10.3122/jabfm.2015.02.140189
Suling F, Patricia M, Suling T. Prevalence and risk factors of patient with acute coronary syndrome at Universitas Kristen Indonesia general hospital. Open Access Macedonian Journal of Medical Sciences. 2018;10:1-4.
Mirza AJ, Taha AY, Khdhir BR. Risk factors for acute coronary syndrome in patients below the age of 40 years. Egypt Hear J. 2018;70(4):233-5. https://doi.org/10.1016/j.ehj.2018.05.005 PMid:30591735 DOI: https://doi.org/10.1016/j.ehj.2018.05.005
Varghese T, Kumar A. Predisposing risk factors of acute coronary syndrome (ACS): A mini review. J Pharm Sci Res. 2019;11(5):1999-2002.
Ralapanawa U, Kumarasiri PV, Jayawickreme KP, Kumarihamy P, Wijeratne Y, Ekanayake M, et al. Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. BMC Cardiovasc Disord. 2019;19(1):229. https://doi.org/10.1186/s12872-019-1217-x PMid:31638908 DOI: https://doi.org/10.1186/s12872-019-1217-x
Kumar D, Ashok A, Saghir T, Khan N, Solangi BA, Ahmed T, et al. Prognostic value of GRACE score for in-hospital and 6 months outcomes after non-ST elevation acute coronary syndrome. Egypt Heart J. 2021;73(1):22. https://doi.org/10.1186/s43044-021-00146-9 PMid:33677742 DOI: https://doi.org/10.1186/s43044-021-00146-9
Mouhat B, Putot A, Hanon O, Eicher JO, Chagué F, Beer JC, et al. Low systolic blood pressure and mortality in elderly patients after. J Am Heart Assoc. 2020;9(5):e013030. https://doi.org/10.1161/JAHA.119.013030 PMid:32098597 DOI: https://doi.org/10.1161/JAHA.119.013030
PERKI. Pedoman Tata Laksana Sindrom Koroner Akut 2018. Perhimpunan Dokter Spesialis Kardiovaskular Indonesia; 2018.
Ma W, Liang Y, Zhu J, Yang Y, Tan H, Yu L, et al. Impact of admission systolic blood pressure and antecedent hypertension on short-term outcomes after ST-segment elevation myocardial infarction: Strobe-compliant article. Medicine (Baltimore). 2015;94(34):e1446. https://doi.org/10.1097/MD.0000000000001446 PMid:26313807 DOI: https://doi.org/10.1097/MD.0000000000001446
Deedwania P, Kosiborod M, Barrett E, Ceriello A, Isley W, Raskin P, et al. Hyperglycemia and acute coronary syndrome: A scientific statement from the American heart association diabetes committee of the council on nutrition, physical activity, and metabolism. Circulation. 2008;117(12):1610-9. https://doi.org/10.1161/CIRCULATIONAHA.107.188629 PMid:18299505 DOI: https://doi.org/10.1161/CIRCULATIONAHA.107.188629
Roohafza H, Talaei M, Pourmoghaddas Z, Rajabi F, Sadeghi M. Association of social support and coping strategies with acute coronary syndrome: A case-control study. J. Cardiol. 2012;59(2):154-9. https://doi.org/10.1016/j.jjcc.2011.12.001 PMid:22266457 DOI: https://doi.org/10.1016/j.jjcc.2011.12.001
Anwar IW, Wijaya IP, Sukrisman L, Nasution SA, Rumende CM. Diagnostic accuracy of platelet/lymphocyte ratio for screening complex coronary lesion in different age group of patients with acute coronary syndrome. Acta Med Indones. 2018;50(3):185-92. PMid:30333267
Dinakrisma AA, Wijaya IP, Nasution SA, Dewiasty E. The role of fragmented QRS (fQRS) as a predictor of major adverse cardiac event within 30 days in acute coronary syndrome patients: A retrospective cohort study. Acta Med. Indones. 2019;51(1):3-9.
Shlomai G, Kopel E, Goldenberg I, Grossman E. The association between elevated admission systolic blood pressure in patients with acute coronary syndrome and favorable early and late outcomes. J Am Soc Hypertens. 2015;9(2):97-103. https://doi.org/10.1016/j.jash.2014.11.005 DOI: https://doi.org/10.1016/j.jash.2014.11.005
Razzolini R, Iannaccone G. Systolic, mean and pulse pressure values in patients with acute coronary syndrome. Minerva Cardiol Angiol. 2021;69(3):277-9. https://doi.org/10.23736/ S2724-5683.20.05434-1 PMid:33427421 DOI: https://doi.org/10.23736/S2724-5683.20.05434-1
Jneid H, Lincoff AM. Acute coronary syndromes. Clevel Clin Found Intens Rev Intern Med. 2014;298:341-2.
Ayhan H, Durmaz T, Keleş T, Bayram NA, Bilen E, Akçay M, et al. The relationship between acute coronary syndrome and stress hyperglycemia. Exp Clin Endocrinol Diabetes. 2014;122(4):222-6. https://doi.org/10.1055/s-0034-1367002 PMid:24771010 DOI: https://doi.org/10.1055/s-0034-1367002
Ertorer ME, Haydardedeoglu FE, Erol T, Anaforoglu I, Binici S, Tutuncu NB, et al. Newly diagnosed hyperglycemia and stress hyperglycemia in a coronary intensive care unit. Diabetes Res Clin Pract. 2010;90(1):8-14. https://doi.org/10.1016/j.diabres.2010.05.023 PMid:20674059 DOI: https://doi.org/10.1016/j.diabres.2010.05.023
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Copyright (c) 2022 Sri Haryuni, Chatarina Umbul Wahyuni, Moh Alimansur, Jatmiko Jatmiko, Kun Ika Nur Rahayu, Ani Sutriningsih, Siti Nur Hasina (Author)
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