Case Report Multiple Sclerosis

Ike Retno Yolanda; Kiking Ritarwan

doi:10.3889/oamjms.2022.9241

Authors

Ike Retno Yolanda Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Kiking Ritarwan Department of Neurology

DOI:

https://doi.org/10.3889/oamjms.2022.9241

Keywords:

Sclerosis multiple, Demyelinating, Dissemination in space, Dissemination in time

Abstract

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease in the form of chronic inflammation of the CNS. This disease is mediated by autoreactive lymphocytes that can cross the blood-brain barrier and thus enter the CNS and cause inflammation. Chronic demyelinating CNS lesions characterize multiple sclerosis, and immunity to myelin is involved. This disease predominantly attacks the brain, spinal cord, and optic nerve. The diagnosis of MS is made clinically, and there is no single definitive test for MS. The key to diagnosis is Dissemination in Space (DIS) and Dissemination in Time (DIT). Magnetic resonance imaging has become an essential part of the diagnosis of MS after clinical.

CASE REPORT: Here, we report a case of a 31 year-old woman with the main complaint of weakness of four extremities accompanied by a decreased vision and impaired urination and bowel movement. The patient was diagnosed with suspected MS.

CONCLUSION: The patient subsequently was treated with intravenous steroids and, on the routine follow-up found marked clinical improvement.

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References

Estiasari R. In: Aninditha T, Wiratman W, editors. Multipel Sklerosis. Jakarta: Buku Ajar Neurologi; 2017. p. 249-57.

PERDOSSI. Pedoman Diagnosis dan Tatalaksana Multipel Sklerosis di Indonesia. Jakarta: Badan Penerbit FKUI; 2016.

Ritarwan K. In: Sudewi AA, Sugianto P, Ritarwan K, editors. Parainfection Demielinating of Central Nervous Sistem. Surabaya: Infeksi pada Sistem Saraf; 2011. p. 151-70.

Joseph JP. Diagnosis of Multiple Sclerosis. Kuala Lumpur: IntechOpen; 2019.

Jafar Y. Management of multiple sclerosis. Cermin Dunia Kedokteran. 2017;44(3):180-3.

Hermoye L. Neuroimaging biomarkers in multiple sclerosis. Imagylis. 2004;1:1-4.

Rovira A. Diagnostic of multiple sclerosis. J Belgian Soc Radiol. 2017;101(12):1-2. DOI: https://doi.org/10.5334/jbr-btr.1426

Doshi A, Chataway J. Multiple sclerosis, a treatable disease. Clin Med. 2016;16(6):53-9. https://doi.org/10.7861/clinmedicine.16-6-s53 PMid:27956442 DOI: https://doi.org/10.7861/clinmedicine.16-6-s53

Rizminardo F, Syarief I, Lestari R, Handayani T. Multiple sclerosis in children. J Kesehatan Andalas. 2018;7(4):76-82. DOI: https://doi.org/10.25077/jka.v7i0.927

Huang WJ, Chen WW, Zhang X. Multiple sclerosis: Pathology, diagnosis and treatments (review). Exp Ther Med. 2017;13(6):3163-6. https://doi.org/10.3892/etm.2017.4410 PMid:28588671 DOI: https://doi.org/10.3892/etm.2017.4410

Guarnizo A, Bermudez S, Torres O, Nassar A, Torres C. Diagnosis and evalu ation of multiple sclerosis: What the radiologist should now and report, current concepts. Rev Colomb Radiol. 2016;27(4):4486-91.

Montalban X, Gold R, Thompson AJ, Romero SO, Amato MP, Chandraratna D. ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis. Multipe Sclerosis J. 2018;24(2):96-120. https://doi.org/10.1177/1352458517751049 PMid:29353550 DOI: https://doi.org/10.1177/1352458517751049

Shaw M, Laliberte R. Current strategies in the treatment of multiple sclerosis. Am J Manag Care. 2018;3:3-12.

Kaunzner UW, Gauthier SA. MRI in the assessment and monitoring of multiple sclerosis: An update on best practice. Arch Neurol Disord. 2017;10(6):247-61. https://doi.org/10.1177/1756285617708911 PMid:28607577 DOI: https://doi.org/10.1177/1756285617708911

Fakhredin RB, Saade C, Kerek R, Jamal L, Khoury S, Merhi F. Imaging in multiple sclerosis: A new spin on lesions. J Med Imaging Radiat Oncol. 2016;60:577-86. https://doi.org/10.1111/1754-9485.12498 PMid:27464473 DOI: https://doi.org/10.1111/1754-9485.12498

Fillipi M, Rocca MA, Ciccarelli O, Stefano ND, Evangelou N, Kappos L. MRI criteria for the diagnosis of multiple sclerosis: Magnims consensus guidelines. Lancet Neurol. 2016;15(3):292-303. https://doi.org/10.1016/S1474-4422(15)00393-2 PMid:26822746 DOI: https://doi.org/10.1016/S1474-4422(15)00393-2

Lovblad K, Anzalone N, Dorfler A, Essig M, Hurwitz B, Kapppos L, et al. MR imaging in multiple sclerosis: Review and recommendations for current practice. AJNR Am J Neuroradiol. 2010;31(6):983-9. https://doi.org/10.3174/ajnr.A1906 PMid:20019103 DOI: https://doi.org/10.3174/ajnr.A1906

Ghassemi N, Razavi S, Nikzad E. Multiple sclerosis: Pathogenesis, symptoms, diagnoses and cell-based therapy. Cell J. 2017;19(1):1-10. https://doi.org/10.22074/cellj.2016.4867 PMid:28367411

Ochi H. Clinical features, diagnosis and therapeutic strategies in pediatric multiple sclerosis. Clin Exp Neuroimmunol. 2017;8(S1):33-9. https://doi.org/10.1111/cen3.12347 DOI: https://doi.org/10.1111/cen3.12347

Ropper AH, Samuels MA, Klein JP. Adams and Victor’s Principles of Neurology. 10th ed. New York: McGraw Hill Education; 2014.

Kesselring J, Comi G, Thompson AJ. Multiple Sclerosis: Recovery of Function and Neurorehabilitation. Cambridge: Cambridge University Press; 2010. DOI: https://doi.org/10.1017/CBO9780511781698