Platelet-Rich Plasma: Applications in Cosmetic Dermatology

Boy Ardi Rohanda; Nelva Karmila Jusuf

doi:10.3889/oamjms.2022.9339

Authors

Boy Ardi Rohanda Department of Dermatology and Venerology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia https://orcid.org/0000-0003-3666-8830
Nelva Karmila Jusuf Department of Dermatology and Venerology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.9339

Keywords:

Platelet-rich plasma, Cosmetic dermatology, Growth factor

Abstract

Platelet-rich plasma (PRP) or autologous platelet gel, plasma-rich growth factors, and platelet-concentrated plasma are blood component that is rich in thrombocytes on a small volume of plasma. There were seven primary growth factors that actively secreted by thrombocytes including platelet-derived growth factor, transforming growth factor-β, vascular endothelial growth factor, epidermal growth factor, fibroblast growth factor, connective tissue growth factor, and insulin-like growth factor-1. PRP application in cosmetic dermatology includes tissue regeneration, wound healing, repairing scar tissue, skin rejuvenation, and being used in alopecia patients. PRP could accelerate soft-tissue formation in the subdermal, activate fibroblast formation and new collagen deposition, and formation of blood vessels and fat cells. PRP is also considered a potential therapy for accelerating hair growth for alopecia.

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