The Establishment of the Cause-Effect Relationship of the Formation of Somatic Diseases in the Population of Pre-Aral under the Influence of Ecological Factors

Laylya Seksenova; Bibigul Koshkarbaeva; Zhibek Zhumadilova; Olga Dedova; Nailya Akhmetova; Marina Izmailovich; Anna Knaus; Orynbala Sabekova; Aliya Kabduova; Dina Sarbasova; Sabina Valiyeva; Zhanar Sydykbaeva

doi:10.3889/oamjms.2022.9369

Authors

Laylya Seksenova Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0002-8090-7352
Bibigul Koshkarbaeva Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0001-5509-1040
Zhibek Zhumadilova Collective Use Laboratory of the Research Center, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan
Olga Dedova Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0002-5041-969X
Nailya Akhmetova Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0002-0611-1831
Marina Izmailovich Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0001-8128-4356
Anna Knaus Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0002-5289-7126
Orynbala Sabekova Department of Nurse, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0001-6273-6185
Aliya Kabduova Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan
Dina Sarbasova Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0002-2853-9150
Sabina Valiyeva Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0003-0767-1993
Zhanar Sydykbaeva Department of Internal Diseases, NJSC “Karaganda Medical University,” Karaganda, Kazakhstan https://orcid.org/0000-0001-5621-6589

DOI:

https://doi.org/10.3889/oamjms.2022.9369

Keywords:

Aral sea, Ecological factor, Bronchial asthma, Anemia, Leukopenia, Eczema

Abstract

Aim: The drying out region of the Aral Sea - the largest ecological disaster of anthropogenic origin. Establishment of the cause-and-effect relationship of formation of diseases among the adult population under the influence of environmental-hygienic factors.

Methods: The article identifies the relationship between somatic diseases in the surveyed population and identifies the leading type of aberrations under influence of ecological factors in this region.

Results: The article presents the results of multidimensional statistical analysis (correlation, linear and nonlinear regression, logistic) with the gradual establishment of the presence of the influence of the environmental factor on the development of a particular nosology and determining the significance of this influence, and also the prediction of the incidence growth with an increase in the level of the environmental factor was assessed.

Conclusion: This article provides the leading nosologies from the main classes of diseases throughout the Aral Sea region.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Pivovarov IP, Al-Sabunchi АА, Sheina NI. Problem of unpredictable anthropogenic exposure to the state of natural environment in countries of Southwest Asia. Gig Sanit. 2013;6:21-25. PMid:24624815

Omirbayeva SM, Kulkybayeb GA, Shpakov АE. Problems in the assessment of the risk from environmental factors on the population’s health in the Republic of Kazakhstan. Gig Sanit. 2007;2:3-4.

Aliyev RА. Influence of harmful environmental factors on the incidence of the population of the Republic of Kazakhstan. Hyg Epidemiol Immunol. 2011;3:12-13.

Konstantinov АP. Features of environmental problems in modern conditions and their impact on the health of the population of Russia. Fundam Res. 2004;3:106-8.

Varaksin АN. Statistical Regression-type Models in Ecology and Medicine. Vl. 256. Yekaterinburg: Goshickyi. 2006.

Chebotarev PА. Assessment of the health of the pediatric population living in towns with varying ambient air pollution. Hyg Sanit. 2007:6:76-8.

Wang Q, Ito M, Adams K, Li BU, Klopstock T, Maslim A, et al. Mitochondrial DNA control region sequence variation in migraine headache and cyclic vomiting syndrome. Am J Med Genet A. 2004;131(5):50-8. PMid:15368478 DOI: https://doi.org/10.1002/ajmg.a.30323

Sabirov Z, Namazbaeva Z, Battakova S, Otarbayeva M, Mukasheva M, Yeshmagambetova A. Chemical mutagenesis and cytogenetic chromosomal abnormalities in a population living in the aral Sea region. Open Access Maced J Med Sci. 2020;8(E):544-50. https://doi.org/10.3889/oamjms.2020.5345 DOI: https://doi.org/10.3889/oamjms.2020.5345

Ibraeva LK, Amanbekova AU, Zhanbasinova NM, Sexenova LS, Rybalkina DH, Salimbayeva BM, et al. Epidemiological aspects of morbidity in the class of digestive organs in Kazakhstan. Ter Arkh. 2018;90(2):75-8. https://doi.org/10.26442/terarkh201890275-78 PMid:30701777 DOI: https://doi.org/10.26442/terarkh201890275-78

Markova IV, Afanasiev VВ, Cybulkin EК. Clinical Toxicology of Children and Adolescents. Vol. 400. St. Petersburg: Alexander Beglov, Intermedica; 1999.

Mufazalova NA. Pharmacological correction of immuno and hepatotoxic effects of xenobiotics. Diss Dr Med Sci Ufa. 2002;9:14.

Grishchenko SV, Grishchenko II, Avakumova AV. Hygienic assessment of the state of the environment of the Donetsk region and the degree of its danger to public health. Bull Hyg Epidemiol. 2007;1:812.

Gromova OA, Torshin IY, Oshchepkova EV. Is it possible to prevent vascular calcification with calcium and Vitamin D3 preparations? Zemsky Doctor. 2011;3(7):17-25.

Melnikova NV, Kantur VА. Non-pharmacological Prophylaxis of Helio-meteotropic Reactions in Patients with Chronic Nonspecific Lung Diseases. Adaptation to Extreme Geophysical Factors and Prophylaxis of Meteotropic Reactions. Mat Region Symposium Novosibirsk; 1989. p. 191-4.

Ye P, Harlamova NF. The influence of abiotic factors for patients with bronchial asthma. Biology. 2004;3(33):98-9.

Ye P. The influence of meteorological factors for patients with bronchial asthma. Biology. 2004;3(33):84-6.

Dotsenko EА, Prishepa IМ, Krestianinova TY. Weather and climatic conditions and current broncial asthma. Immunopathol Allergol Infectol. 2004;4:84-91.

Bronchial Asthma. Global Strategy. Pulmonology; 1996. p. 161.

Gnateiko ОZ, Lukyanenko NS. Ecogenetic aspects of human pathology, caused by the influence of harmful factors of the environment. Childs Health. 2007;6(9):82-7.

Ostropolec SS. Myocardium. In: Structure and Function in Norm and Pathology. Donetsk: Nord Press; 2007. p. 212.

Skalnyi АV, Rudakov IА. Bioelements in Medicine. Tutorial M. Onyx 21st Century, World; 2004. p. 272.