The Current State and Prospects for the Use of Herbal Medicines for Wound-Healing and Anti-Inflammatory Action in Kazakhstan: A Literature Review

Aigul Medeshova; Perizat Orazbayeva; Ainur Romanova; Nuripa Dildabekova; Bekzhan Orazbayev; Bibigul Ashirbekova; Anar Bokenovna

doi:10.3889/oamjms.2022.9426

Authors

Aigul Medeshova School of Pharmacy, Karaganda Medical University, Karaganda, Kazakhstan
Perizat Orazbayeva School of Pharmacy, Karaganda Medical University, Karaganda, Kazakhstan https://orcid.org/0000-0003-4314-6942
Ainur Romanova Department of Clinical Pharmacology and Evidence-Based Medicine, Karaganda Medical University, Karaganda, Kazakhstan
Nuripa Dildabekova Department of Clinical Pharmacology and Evidence-Based Medicine, Karaganda Medical University, Karaganda, Kazakhstan
Bekzhan Orazbayev Department of Oncology and Radiation Diagnostics, Karaganda Medical University, Karaganda, Kazakhstan https://orcid.org/0000-0001-7207-1973
Bibigul Ashirbekova School of Pharmacy, Karaganda Medical University, Karaganda, Kazakhstan
Anar Bokenovna Department of Kazakh Language and Culture, Karaganda Technical University, Karaganda, Kazakhstan

DOI:

https://doi.org/10.3889/oamjms.2022.9426

Keywords:

Medicinal plants, Wound-healing action, Anti-inflammatory action, Dosage forms

Abstract

BACKGROUND: As dosage forms, oils, drops, ointments, solutions, films, and suppositories represent phytopreparations for external use. The use of the drug “Kyzyl mai” in clinical practice pursues the achievement of wound-healing (including anti-burn effect), anti-inflammatory, reparative, metabolic, antibacterial, antiviral, and analgesic effects.

AIM: We aimed to analyze the range of soft dosage forms in the form of suppositories with herbal components in their composition, used as anti-inflammatory and wound-healing agents.

METHODS: The design in this study was a literature review article. Search for articles using relevant ones obtained from data based on PubMed, Scopus, Web of Science, ScienceDirect, and Google Scholar obtained 283 articles.

RESULTS: There are 12 articles that are relevant and discuss their content and use in the health.

CONCLUSION: This review presents new dosage forms have been created – medicinal film “Fiadent,” medicinal film “Normophyt,” medicinal film with Piyavit. On the basis of chamomile extract obtained by supercritical carbon dioxide extraction, the optimal composition and technological scheme for the production of anti-inflammatory suppositories for use in proctology have been developed. The article describes a literature review of suppositories of anti-inflammatory action based on essential oil of balsamic poplar buds which have been developed.

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