Evaluation of Lung Cancer Incidence Dynamics in Kyrgyzstan

Aliia Bazhanova; Stalbek Akhunbaev; Enverbek Soodonbekov; Gaukhar Nurtazinova; Zhansaya Telmanova; Nurbek Igissinov

doi:10.3889/oamjms.2022.9965

Authors

Aliia Bazhanova Department of Macro- and Microanatomy, International Higher School of Medicine, Bishkek, Kyrgyzstan; 2Department of Science, Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan
Stalbek Akhunbaev Department of Macro- and Microanatomy, International Higher School of Medicine, Bishkek, Kyrgyzstan
Enverbek Soodonbekov Department of Science, Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan; Department of Epidemiology and Prevention of Malignant Neoplasms, National Center for Oncology and Hematology, Bishkek, Kyrgyzstan
Gaukhar Nurtazinova Department of Public Health, Central Asian Institute for Medical Research, Nur-Sultan, Kazakhstan; Department of Surgical Diseases with a course of Cardiothoracic and Maxillofacial Surgery, Astana Medical University, Nur-Sultan, Kazakhstan
Zhansaya Telmanova Department of Science, Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan; Department of Public Health, Central Asian Institute for Medical Research, Nur-Sultan, Kazakhstan; Department of Surgical Diseases with a course of Cardiothoracic and Maxillofacial Surgery, Astana Medical University, Nur-Sultan, Kazakhstan https://orcid.org/0000-0002-2364-6520
Nurbek Igissinov Department of Science, Eurasian Institute for Cancer Research, Bishkek, Kyrgyzstan; Department of Public Health, Central Asian Institute for Medical Research, Nur-Sultan, Kazakhstan; Department of Surgical Diseases with a course of Cardiothoracic and Maxillofacial Surgery, Astana Medical University, Nur-Sultan, Kazakhstan

DOI:

https://doi.org/10.3889/oamjms.2022.9965

Keywords:

Lung cancer, Incidence, Component analysis, Kyrgyzstan

Abstract

Background: In 2020, more than half of all cases (59.6%) of lung cancer of both sexes and 61.9% of lung cancer deaths were registered in Asia. In Kyrgyzstan, lung cancer is the second most common cancer after stomach cancer (11.2% of all diagnosed malignancies).

Objective: The study is to conduct a component analysis of the dynamics of the incidence of lung cancer (LC) in Kyrgyzstan.

Methods: Primary data were for registered patients with LC (ICD 10 – C34) in the whole country during the period of 2010-2019. Evaluation of changes in LC incidence in the population of Kyrgyzstan was performed using component analysis according to the methodological recommendations.

Results: The study period, 4,931 new cases of LC were recorded. During the studied years an average age of patients with lung cancer was 61.4 years (95%CI=60.9-61.9). Age-related indicators of the incidence of LC had a peak in 65+ years in both sexes (84.9±3.2⁰/₀₀₀₀), male (159.5±6.4⁰/₀₀₀₀) and female (35.5±2.2⁰/₀₀₀₀) population. Trends in the ASIR of LC in the entire population tended to decrease in all age groups. The incidence rate decreased from 8.0⁰/₀₀₀₀ (2010) to 7.2⁰/₀₀₀₀ in 2019 and the overall decline was −0.8⁰/₀₀₀₀, including due to the age structure – ∑Δ_A=+1.2⁰/₀₀₀₀, due to the risk of acquiring illness – ∑Δ_R=−1.8⁰/₀₀₀₀ and their combined effect – ∑Δ_AR=−0.2⁰/₀₀₀₀. The component analysis revealed that the increase in the number of patients with LC was mainly due to the growth of the population (Δ_P=+17.9%), changes in its age structure (Δ_A=+15.4%).

Conclusion: In the Republic of Kyrgyzstan, the incidence of lung cancer is decreasing. According to the component analysis, in general, the increase in the number of patients was due to demographic factors, while the decrease in morbidity was influenced by a decrease in the risk of acquiring illness. The implementation of the results of this study is recommended in the management of anticancer measures for lung cancer.

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