Incidence of Thrombocytopenia in Idiopathic Hyperbilirubinemic Newborns

Authors

  • Hassan Boskabadi Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad
  • Shahin Mafinezhad Department of Pediatrics, North Khorasan University of Medical Sciences, Bojnurd
  • Fatemah Bagher Faculty of Nursing and Midwifery, Mashhad Azad University of Medical Science
  • Yasaman Bozorgnia Department of Orthodontics, North Khorasan University of Medical Sciences, Bojnurd

DOI:

https://doi.org/10.3889/oamjms.2014.043

Keywords:

newborn, hyperbilirubinemia, thrombocytopenia, incidence.

Abstract

Background: Hyperbilirubinemia is the most common reason for admission during the neonatal period and may develop serious complications. Thrombocytopenia is defined as platelet count <150,000/mm3 and has not been conclusively reported as a complication of hyperbilirubinemia in any of the standard paediatric textbooks. The aim of this study was to find the incidence of thrombocytopenia in neonates with idiopathic jaundice and the relationship between hyperbilirubinaemia and platelet count.

Methods: This was a descriptive-analytic study accomplished on 878 newborns. After a detailed history, clinical examination and baseline investigations,185 babies with idiopathic hyperbilirubinemia were tested for platelet counts and then categorized in two groups namely group A (n=65) and group B (n=120) showing the presence and absence of thrombocytopenia, respectively. Newborns data were recorded and Statistical analysis was carried out, using SPSS 11.5.

Results: The incidence of thrombocytopenia was seen in 65 (12%) newborns admitted due to jaundice. The mean serum bilirubin in group A and B was defined as 19.7 (± 6) and 20.4 (± 5), respectively (P = 0.362).There was no significant difference in Laboratory variables likeTSH, T4, coombs test, reticulocite count, serum sodium and hematocrit values between two groups.

Conclusion: This study determines higher rate of thrombocytopenia among idiopathic hyperbilirubinemic neonates (36%) and helps the practitioner to be aware of this association and avoid unnecessary investigations.We did not find a significant correlation between serum bilirubin values and thrombocytopenia.

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References

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Published

2014-06-15

How to Cite

1.
Boskabadi H, Mafinezhad S, Bagher F, Bozorgnia Y. Incidence of Thrombocytopenia in Idiopathic Hyperbilirubinemic Newborns. Open Access Maced J Med Sci [Internet]. 2014 Jun. 15 [cited 2024 Mar. 28];2(2):261-4. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2014.043

Issue

Section

B - Clinical Sciences