Impact of Platelet-Rich Plasma on Bone Height Changes around Platform Switched Implants Supporting Mandibular Overdentures in Controlled Diabetic Patients
DOI:
https://doi.org/10.3889/oamjms.2015.126Keywords:
Dental implant, platform switching, platelet-rich-plasma, CBCT, crestal bone remodeling, osseointegrationAbstract
BACKGROUND: The platform switching concept was recently introduced to implant dentistry involving the reduction of restoration abutment diameter with respect to the diameter of dental implant. Long-term follow-up around these implants showed higher levels of bone preservation and proper stress distribution and improved esthetics.
AIM: The aim of the present study was to evaluate the changes in bone height by means of radiographic examination around platform switched implant supporting mandibular overdentures in controlled diabetic patients.
SUBJECTS AND METHODS: Fourteen male complete edentulous patients were selected and enrolled in a follow-up study plan. Split mouth technique was applied; one side implant chosen randomly with Platelet-rich-plasma (PRP) and the other without PRP, bone height changes was assessed by Cone Beam Computed Tomography (CBCT) radiographic examination after 3 months, 6 months, 9 months and 1 year later.
RESULTS: There was increase in bone height loss in both sides but with no statistical significance difference between the two sides after 3 months, 6 months, 9 months and 1 year respectively.
CONCLUSION: The result of this article satisfied the patients both esthetically and functionally with recorded increase in bone height loss.Downloads
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Del Corso M, Vervelle A, Simonpieri A, et al. Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) oral and maxillofacial in surgery part 1: Periodontal and dentoalveolar surgery. Curr Pharm Biotechnol. 2012;13:1207-1230.
http://dx.doi.org/10.2174/138920112800624391 DOI: https://doi.org/10.2174/138920112800624391
PMid:21740371
Simonpieri A, Del Corso M, Vervelle A, Jimbo R, Inchingolo F, Sammartino G, Dohan Ehrenfest DM. Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 2: Bone graft, implant and reconstructive surgery. Curr Pharm Biotechnol. 2012;13(7):1231-56.
http://dx.doi.org/10.2174/138920112800624472 DOI: https://doi.org/10.2174/138920112800624472
PMid:21740370
Ehrenfest DM, Bielecki T, Mishra A, et al. In search of a consensus terminology in the field of platelet concentrates for surgical use: platelet-rich plasma (PRP), platelet-rich fibrin (PRF), fibrin gel polymerization and leukocytes. Curr Pharm Biotechnol. 2012;13:1131-1137.
http://dx.doi.org/10.2174/138920112800624328 DOI: https://doi.org/10.2174/138920112800624328
Anitua EA, Orive G, Aguirre JJ, Andia I. Clinical outcome of immediately loaded dental implants bioactivated with plasma rich in growth factors:A five-year retrospective study. J Periodontol. 2008;79:1168–76.
http://dx.doi.org/10.1902/jop.2008.070580 DOI: https://doi.org/10.1902/jop.2008.070580
PMid:18597598
Nikolidakis D, Van den Dolder J, Wolke JG, Jansen JA.The effect of platelet-rich plasma on the early bone formation around Ca-P coated and non-coated oral implants in cortical bone. Clin Oral Impl Res. 2008;19:207–13.
http://dx.doi.org/10.1111/j.1600-0501.2007.01456.x DOI: https://doi.org/10.1111/j.1600-0501.2007.01456.x
PMid:18067601
Wagenberg B, Froum SJ. Prospective study of 94 platform-switched implants observed from 1992 to 2006. Int J Periodontics Restorative Dent. 2010;30:9-17.
PMid:20224827
Casap N, Laviv A, Wexler A. Computerized navigation for immediate loading of dental implants with a pre-fabricated metal frame: A feasibility study. J Oral Maxillofac Surg. 2011;69:512–9.
http://dx.doi.org/10.1016/j.joms.2010.10.031 DOI: https://doi.org/10.1016/j.joms.2010.10.031
PMid:21238848
Covani U, Marconcini S, Crespi R, Barone A. Bacterial plaque colonization around dental implant surfaces. Implant Dent. 2006;15:298-304.
http://dx.doi.org/10.1097/01.id.0000226823.58425.19 DOI: https://doi.org/10.1097/01.id.0000226823.58425.19
PMid:16966904
Enkling N, Johren P, Klimberg V, Bayer S, Mericske-Stern R, Jepsen S. Effect of platform switching on peri-implant bone levels: a randomized clinical trial. Clin Oral Implants Res. 2011;22:1185-1192.
http://dx.doi.org/10.1111/j.1600-0501.2010.02090.x DOI: https://doi.org/10.1111/j.1600-0501.2010.02090.x
PMid:21320171
Cumbo C, Marigo L, Somma F, La Torre G, Minciacchi I, D'Addona A. Implant platform switching concept: literature review. Eur Rev Med Pharmacol Sci. 2013;17(3):392-7.
PMid:23426544
Degidi M, Nardi D, Piatteli A. Immediate loading of the edentulous maxilla with a final restoration supported by an intraoral welded titanium bar: acasa series of 20 consecutive cases. J Periodontol. 2008;79:2207-2213.
http://dx.doi.org/10.1902/jop.2008.080141 DOI: https://doi.org/10.1902/jop.2008.080141
PMid:18980531
Lazzara RJ, Porter SS. Platform switching: a new concept in implant dentistry for controlling post-restorative crestal bone levels. Int J Periodontics Restorative Dent. 2006;26: 9-1.
PMid:16515092
Astrand P, Engquist B, Dahlgren S, Gröndahl K, Engquist E, Feldmann H. Astra Tech and Branemark system implants: a 5-year prospective study of marginal bone reactions. Clin Oral Implants Res. 2004;15:413-420.
http://dx.doi.org/10.1111/j.1600-0501.2004.01028.x DOI: https://doi.org/10.1111/j.1600-0501.2004.01028.x
PMid:15248875
Prasad DK, Shetty M, Bansal N, Hegde C. Crestal bone preservation: a review of different approaches for successful implant therapy. Indian Journal of Dental Research. 2011;22(2):317–323.
http://dx.doi.org/10.4103/0970-9290.84311 DOI: https://doi.org/10.4103/0970-9290.84311
PMid:21891906
Jung RE, Schmoekel HG, Zwahlen R, Kokovic V, Hammerle CHF, Webber FE. Platelet-rich plasma and fibrin as delivery systems for rhBMP-2. Clin Oral Impl Res. 2005;16:676–82.
http://dx.doi.org/10.1111/j.1600-0501.2005.01183.x DOI: https://doi.org/10.1111/j.1600-0501.2005.01183.x
PMid:16307574
Roffi et al. Does PRP enhance bone integration with grafts, graft substitutes, or implants? A systematic review. BMC Musculoskeletal Disorders. 2013;14:330.
http://dx.doi.org/10.1186/1471-2474-14-330 DOI: https://doi.org/10.1186/1471-2474-14-330
PMid:24261343 PMCid:PMC3870962
HÏ‹rzeler M, Fickl S, Zuhr O, Wachtel HC. Peri-implant bone level around implants with platform switched abutments: preliminary data from a prospective study. J Oral Maxillofac Surg. 2007;65(7 Suppl 1):33-39.
http://dx.doi.org/10.1016/j.joms.2007.03.024 DOI: https://doi.org/10.1016/j.joms.2007.03.024
PMid:17586347
Zechner W, Tangi S, Tepper G, Fürst G, Bernhart T, Haas R. Influence of platelet-rich plasma on osseous healing of dental implants: A histologic and histomorphometric study in minipigs. Int J Oral Maxillofac Implants. 2003;18:15–22.
PMid:12608664
Hegab A, Shuman M. Efficacy of Platelet-Rich Plasma in Reduction of the Resorption of the Alveolar Cleft Bone Graft. A Comparative Study. Dentistry. 2012;2(7):2161-1122.
http://dx.doi.org/10.4172/2161-1122.1000150 DOI: https://doi.org/10.4172/2161-1122.1000150
Mariano R, De Melo W and Avelino C. Comparative Radiographic Evaluation of Alveolar Bone Healing Associated With Autologous Platelet-Rich Plasma After Impacted Mandibular Third Molar Surgery. J Oral Maxillofac Surg. 2012;70:19-2.
http://dx.doi.org/10.1016/j.joms.2011.03.028 DOI: https://doi.org/10.1016/j.joms.2011.03.028
PMid:21778014
Paul et al. Application of Platelet-Rich Plasma for Enhanced Bone Regeneration in Grafted Sinus. J Oral Maxillofac Surg. 2012;70:657-664.
http://dx.doi.org/10.1016/j.joms.2011.04.027 DOI: https://doi.org/10.1016/j.joms.2011.04.027
PMid:21840102
Peeran S, Alsaid F. Platelet Rich Plasma, Is It Of Use In Human Intrabony Periodontal Defects? International Journal of Science and Technology Research. 2013;2(3):5.
Albanese et al. Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone Regeneration. Immunity and aging. 2013;10:23.
http://dx.doi.org/10.1186/1742-4933-10-23 DOI: https://doi.org/10.1186/1742-4933-10-23
PMid:23763951 PMCid:PMC3683340
Donati M, La Scala V, Billi M, Di Dino B, Torrisi P, Berglundh T. Immediate functional loading of implants in single tooth replacement: A prospective clinical multicenter study. Clin Oral Impl Res. 2008;19:740–8.
http://dx.doi.org/10.1111/j.1600-0501.2008.01552.x DOI: https://doi.org/10.1111/j.1600-0501.2008.01552.x
PMid:18507667
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