Ultrasonographic Enthesopathy and Disease Activity in Psoriatic Arthritis

Authors

  • Mohieldin M. Ahmed Physical Medicine and Rehabilitation Department, Amiri Hospital, Ministry of Health
  • Gehan Gamal Elolemy Rehabilitation and Rheumatology Department, Faculty of Medicine, Benha University
  • Aziz K. Alfeeli Physical Medicine and Rehabilitation Department, Amiri Hospital, Ministry of Health
  • Ayyoub B. Baqer Physical Medicine and Rehabilitation Department, Al-Farwania Hospital, Ministry of Health
  • Adela M. Gad Internal Medicine Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo

DOI:

https://doi.org/10.3889/oamjms.2017.070

Keywords:

Psoriatic arthritis, Ultrasonographic enthesopathy, Psoriatic Activity

Abstract

BACKGROUND: To our knowledge, the correlation between ultrasonographic enthesopathy and severity in psoriatic arthritis (PsA) has been done before. However, the correlation between ultrasonography of enthesopathy and the Psoriatic Arthritis Disease Activity Score (PASDAS) have not been done.

AIM: To compare the results of ultrasonographic enthesopathy of foot and PASDAS in PsA.

MATERIALS AND METHODS: A total of 65 PsA patients were involved and divided into two groups. The first group of 35 active PsA and the second group of 30 ages and sex matched inactive PsA as a control group were recruited in this study. Both groups were evaluated by examination, radiological findings and ultrasonography.

RESULTS: Of 70 entheses in 35 active PsA patients, the most entheseal abnormalities were tender plantar fascia (18.5%), tender Achilles tendon (37.8%). PASDAS was a direct highly significant correlated with plantar fascia and Achilles tendon thickness in in active PsA (r = 0.823 and r = 0.796, p < 0.001 respectively).

CONCLUSION: Musculoskeletal US is an accurate and low-cost method for assessment of enthesopathy with significant correlation to disease activities in psoriatic arthritis.

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References

Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, Cats A, Dijkmans B, Olivieri I, Pasero G, et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 1991; 34:1218-27. https://doi.org/10.1002/art.1780341003 PMid:1930310

Rudwaleit M, Landewe R, van der Heijde D, Listing J, Brandt J, Braun J,Burgos- Vargas R, Collantes-Estevez E, Davis J, Dijkmans B, et al. The development of Assessment of Spondylo Arthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis. 2009; 68(6):770-6. https://doi.org/10.1136/ard.2009.108217 PMid:19297345

Dailey J. Differential diagnosis and treatment of heel pain. Clinics in Podiatry Medicine and Surgery. 1991; 8(1):153–166. PMid:2015526

Galluzzo E, Lischi DM, Taglione E, Lombardini F, Pasero G, Perri G, Riente L. Sonographic analysis of the ankle in patients with psoriatic arthritis. Scand J Rheumatol. 2000; 29:52-5. https://doi.org/10.1080/030097400750001806 PMid:10722258

Healy PJ, Helliwell PS. Measuring clinical enthesitis in psoriatic arthritis: assessment of existing measures and development of an instrument specific to psoriatic arthritis. Arthritis Rheum. 2008; 59(5):686-91. https://doi.org/10.1002/art.23568 PMid:18438903

Kamel M, Eid H, Mansour R. Ultrasound detection of knee patellar enthesitis: a comparison with magnetic resonance imaging. Ann Rheum Dis 2004; 63:213–4. https://doi.org/10.1136/ard.2003.010314 PMid:14722216 PMCid:PMC1754891

Helliwell PS, FitzGerald O, Fransen J, Gladman DD, Kreuger GG, Callis-Duffin K, et al. The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project). Ann Rheum Dis. 2013; 72:986–91. https://doi.org/10.1136/annrheumdis-2012-201341 PMid:22798567

Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H. Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum. 2006; 54(8):2665-73. https://doi.org/10.1002/art.21972 PMid:16871531

Ware JE. Measuring patients' views: the optimum outcome measure. BMJ. 1993; 306:1429–30. https://doi.org/10.1136/bmj.306.6890.1429 PMid:8518638 PMCid:PMC1677908

Acquacalda E, Albert C, Montaudie H, Fontas E, Danre A, Roux CH, Breuil V, Lacour JP, Passeron T, Ziegler LE. Ultrasound study of entheses in psoriasis patients with or without musculoskeletal symptoms: A prospective study. Joint Bone Spine. 2015 Jul;82(4):267-71. https://doi.org/10.1016/j.jbspin.2015.01.016 PMid:25881759

Kavanaugh A and Cassell S. The assessment of disease activity and outcomes in psoriatic arthritis. Clin Exp Rheumatol. 2005; 23 (Suppl. 39):S142-S147. PMid:16273798

Naredo E, Möller I, de Miguel E, Batlle-Gualda E, Acebes C, Brito E, Mayordomo L, Moragues C, Uson J, de Agustín JJ, Martínez A, Rejón E, Rodriguez A,Daudén E. High prevalence of ultrasonographic synovitis and enthesopathy in patients with psoriasis without psoriatic arthritis: a prospective case-control study. Rheumatology (Oxford). 2011; 50(10):1838-48. https://doi.org/10.1093/rheumatology/ker078 PMid:21700682

Yang Q, Qu L, Tian H, Hu Y, Peng J, Yu X, Yu C, Pei Z, Wang G, Shi B, Zhang F, Zhang Y, Zhang F. Prevalence and characteristics of psoriatic arthritis in Chinese patients with psoriasis. J Eur Acad Dermatol Venereol. 2011; 25(12):1409-14. https://doi.org/10.1111/j.1468-3083.2011.03985.x PMid:21349114

Kane D, Stafford L, Bresnihan B, FitzGerald O. Prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience. Rheumatology (Oxford). 2003; 42(12):1460-8. https://doi.org/10.1093/rheumatology/keg384 PMid:14523223

D'Agostino MA, Said-Nahal R, Hacquard-Bouder C, Brasseur JL, Dougados M, Breban M. Assessment of peripheral enthesitis in the spondylarthropathies by ultrasonography combined with power Doppler: a cross-sectional study. Arthritis Rheum. 2003; 48:523-33. https://doi.org/10.1002/art.10812 PMid:12571863

De Filippis LG, Caliri A, Lo Gullo R, Bartolone S, Miceli G, Cannavo SP, Borgia F, Basile G, Aloisi G, Zimbaro G, Scribano E, Bagnato GF. Ultrasonography in the early diagnosis of psoriasis-associated enthesopathy. Int J Tissue React. 2005;27:159–62. PMid:16440579

Ozcakar L, Cetin A, Inanici F, Kaymak B, Gurer CK, Kolemen F. Ultrasonographical evaluation of the Achilles' tendon in psoriasis patients. Int J Dermatol. 2005; 44:930-2. https://doi.org/10.1111/j.1365-4632.2004.02235.x PMid:16336526

De Simone C, Guerriero C, Giampetruzzi AR, Costantini M, Di Gregorio F, Amerio P. Achilles tendinitis in psoriasis: clinical and sonographic findings. J Am Acad Dermatol. 2003; 49:217–22. https://doi.org/10.1067/S0190-9622(03)00904-6

Perrotta FM, Astorri D, Zappia M, Reginelli A, Brunese L, Lubrano E. An ultrasonographic study of enthesis in early psoriatic arthritis patients naive to traditional and biologic DMARDs treatment. Rheumatol Int. 2016; 36(11):1579-1583. https://doi.org/10.1007/s00296-016-3562-8 PMid:27600991

Girolomoni G, Gisondi P. Psoriasis and systemic inflammation: underdiagnosed enthesopathy. J Eur Acad Dermatol Venereol. 2009;23 Suppl 1:3-8. https://doi.org/10.1111/j.1468-3083.2009.03361.x PMid:19686379

Aydin SZ1, Ash ZR, Tinazzi I, Castillo-Gallego C, Kwok C, Wilson C, Goodfield M, Gisondi P, Tan AL, Marzo-Ortega H, Emery P, Wakefield RJ, McGonagle DG. The link between enthesitis and arthritis in psoriatic arthritis: a switch to a vascular phenotype at insertions may play a role in arthritis development. Ann Rheum Dis. 2013; 72(6):992-5. https://doi.org/10.1136/annrheumdis-2012-201617 PMid:22863575

Gisondi P, Tinazzi I, El-Dalati G, Gallo M, Biasi D, Barbara LM, Girolomoni G. Lower limb enthesopathy in patients with psoriasis without clinical signs of arthropathy: a hospital-based case-control study. Ann Rheum Dis. 2008; 67: 26-30. https://doi.org/10.1136/ard.2007.075101 PMid:17720726

Gutierrez M, Filippucci E, De Angelis R, Salaffi F, Filosa G, Ruta S, Bertolazzi C, Grassi W. Subclinical entheseal involvement in patients with psoriasis: an ultrasound study. Semin Arthritis Rheum. 2011; 40(5):407-12. https://doi.org/10.1016/j.semarthrit.2010.05.009 PMid:20688358

Ash ZR, Tinazzi I, Gallego CC, Kwok C, Wilson C, Goodfield M, Gisondi P, Tan AL, Marzo-Ortega H, Emery P, Wakefield RJ, McGonagle DG, Aydin SZ . Psoriasis patients with nail disease have a greater magnitude of underlying systemic subclinical enthesopathy than those with normal nails. Ann Rheum Dis. 2012;71(4):553-6. https://doi.org/10.1136/annrheumdis-2011-200478 PMid:22156725

McGonagle D, Stockwin L, Isaacs J, Emery P. An enthesitis based model for the pathogenesis of spondyloarthropathy. Additive effects of microbial adjuvant and biomechanical factors at disease sites. J Rheumatol. 2001;28:2155–9. PMid:11669149

Mease P. Update on treatment of psoriatic arthritis. Bull NYU Hosp Jt Dis. 2012;70(3):167-71. PMid:23259623

Coates LC, Anderson RR, Fitzgerald O, Gottlieb AB, Kelly SG, Lubrano E, McGonagle DG, Olivieri I, Ritchlin CT, Tan AL, De Vlam K, Helliwell PS. Clues to the Pathogenesis of Psoriasis and Psoriatic Arthritis from Imaging: A Literature Review. The Journal of Rheumatology. 2008; 35:7.

Published

2017-08-11

How to Cite

1.
Ahmed MM, Elolemy GG, Alfeeli AK, Baqer AB, Gad AM. Ultrasonographic Enthesopathy and Disease Activity in Psoriatic Arthritis. Open Access Maced J Med Sci [Internet]. 2017 Aug. 11 [cited 2024 Jul. 2];5(5):651-6. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.070

Issue

Section

B - Clinical Sciences

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