Multiple Primary Acral Lentiginous Melanomas (MPALM)
DOI:
https://doi.org/10.3889/oamjms.2017.162Keywords:
melanoma, multiple primary tumours, acral located tumours, amputations, stagingAbstract
We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolated from current literature; however, that appropriate management of these patients, including staging work and surgical intervention, is to be determined by the individual characteristics of the melanoma and the patient's concomitant risk factors, if any.Downloads
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Asgari MM, Shen L, Sokil MM, Yeh I, Jorgenson E. Prognostics factors and survival in acral lentiginous melanoma. Br J Dermatol. 2017 Apr 22. https://doi.org/10.1111/bjd.15600
Kuchelmeister C, Schaumburg-Lever G, Garbe C. Acral cutaneous melanoma in Caucasians: clinical features, histopathology and prognosis in 112 patients. Br J Dermatol. 2000; 143(2):275-80. https://doi.org/10.1046/j.1365-2133.2000.03651.x PMid:10951133
Bradford PT, Goldstein AM, McMaster ML, Tucker MA. Acral lentiginous melanoma: incidence and survival patterns in the United States, 1986-2005. Arch Dermatol. 2009; 145(4):427-34. https://doi.org/10.1001/archdermatol.2008.609 PMid:19380664 PMCid:PMC2735055
Nam KW, Bae YC, Nam SB, Kim JH, Kim HS, Choi YJ.Characteristics and Treatment of Cutaneous Melanoma of the Foot. Arch Plast Surg. 2016; 43(1):59-65. https://doi.org/10.5999/aps.2016.43.1.59 PMid:26848447 PMCid:PMC4738130
Hayes AJ, Clark MA, Harries M, Thomas JM. Management of in-transit metastases from cutaneous malignant melanoma. Br J Surg. 2004; 91(6):673-82. https://doi.org/10.1002/bjs.4610 PMid:15164434
Lacruz G, Cárdenas I, Carrera C, DÃaz A, Puig-Butillè JA, Badenas C, Malvehy J, Puig S. Multiple primary acral melanomas in two young caucasian patients. Dermatology. 2014;228(4):307-10. https://doi.org/10.1159/000362207 PMid:24942556
Hutcheson AC, McGowan JW 4th, Maize JC Jr, Cook J. Multiple primary acral melanomas in African-Americans: a case series and review of the literature. Dermatol Surg. 2007;33(1):1-10. https://doi.org/10.1097/00042728-200701000-00001
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