The Effect of Gaseous Ozone in Infected Root Canal


  • Nexhmije Ajeti Department of Endodontic and Dental Pathology, Dental Branch, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo
  • Teuta Pustina-Krasniqi Department of Prosthetic Dentistry, Dental Branch, Faculty of Medicine, University of Prishtina (UP), Vice Rector for International Affairs in UP, Prishtina, Kosovo
  • Sonja Apostolska Department of Endodontic and Dental Pathology, Dental Faculty, University of Skopje, Skopje
  • Edit Xhajanka Faculty of Dental Medicine, Prosthodontic Department, Tirana



Antibacterial Effect, CHX, Gaseous Ozone, NaCl, NaOCl, Root Canal


OBJECTIVES: During the treatment of chronic apical periodontitis and pulp necrosis the main role is to irrigate the root canal.

AIM: The aim of this in vivo study was to irrigate with 0.9% NaCl (Natrium Chloride), 2.5 % NaOCl (Sodium Hypochlorite Solution, Sigma Aldrich - Germany) and 2% CHX (Chlorhexidine Digluconate Solution, Sigma Aldrich - Spain) combined with Gaseous Ozone (Prozone WH, Austria).

MATERIAL AND METHODS: This study was realised in the University Dentistry Clinical Centre of Kosovo (UDCCK), respectively in the Department of Endodontic and Dental Pathology, Dental Branch, Faculty of Medicine, Prishtina, Kosovo. The 40 subjects involved in this study belonged to both genders, in age between 15 -65 years. The sample selection was randomised. The retroalveolar radiography for each patient was taken in the suspected tooth. As a therapeutic plan the authors decided to disinfect the root canal with the irrigants, as follows: 2.5 % NaOCl, 2 % CHX and gaseous ozone.

RESULTS: The statistical analyses were based on Kruskal - Vallis test, X - test, DF = 3, r < 0.01. In the isolated average number of the aerobe and anaerobe bacteria colonies, when gaseous ozone was used, there was the significant statistical difference.

CONCLUSIONS: When gaseous ozone was combined with irrigants 0.9%, 2.5 % NaOCl and 2% CHX, it was concluded that the number of colonies of aerobic and anaerobic bacteria was reduced.


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How to Cite

Ajeti N, Pustina-Krasniqi T, Apostolska S, Xhajanka E. The Effect of Gaseous Ozone in Infected Root Canal. Open Access Maced J Med Sci [Internet]. 2018 Feb. 14 [cited 2023 Oct. 3];6(2):389-96. Available from:



D - Dental Sciences

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