Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience

Thuong Nguyen Van; Hien Le Thanh; Tan Nguyen Manh; Phuong Pham Thi Minh; Kiem Pham Cao; SÆ¡n Nguyen Hong; Nghi Dinh Huu; Van Tran Cam; My Le Huyen; Khang Tran Hau; Marco Gandolfi; Francesca Satolli; Claudio Feliciani; Michael Tirant; Aleksandra Vojvodic; Torello Lotti

doi:10.3889/oamjms.2019.001

Authors

Thuong Nguyen Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Hanoi, Vietnam
Hien Le Thanh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Tan Nguyen Manh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Phuong Pham Thi Minh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Kiem Pham Cao National Hospital of Dermatology and Venereology, Hanoi, Vietnam
SÆ¡n Nguyen Hong National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Nghi Dinh Huu National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Van Tran Cam National Hospital of Dermatology and Venereology, Hanoi, Vietnam
My Le Huyen National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Khang Tran Hau National Hospital of Dermatology and Venereology, Hanoi, Vietnam
Marco Gandolfi Clinica Dermatologica, UniversitÃ degli studi di Parma
Francesca Satolli Unit of Dermatology, University of Parma, Parma, Italy
Claudio Feliciani Unit of Dermatology, University of Parma, Parma, Italy
Michael Tirant University of Rome G. Marconi, Rome, Italy; Psoriasis Eczema Clinic, Melbourne, Australia
Aleksandra Vojvodic Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia
Torello Lotti University of Rome G. Marconi, Rome, Italy

DOI:

https://doi.org/10.3889/oamjms.2019.001

Keywords:

Nevus sebaceous, Sebaceous, Nevus, Epidermal nevus

Abstract

BACKGROUND: Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%).

AIM: The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy.

METHODS: Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision.

RESULTS: Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment.

CONCLUSION: Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS.