The Effectiveness of Narrow Band Uvb (Nb-Uvb) In the Treatment of Pityriasis Lichenoides Chronica (PLC) In Vietnam

Authors

  • Doanh Le Huu National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Vietnam
  • Thao Ngo Minh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Thuong Nguyen Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Vietnam
  • Phuong Pham Thi Minh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Nghi Dinh Huu National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Vietnam
  • Van Tran Cam National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • My Le Huyen National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Minh Vu Nguyet National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Vietnam
  • Mai Le Thi National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Hien Do Thi Thu National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Khang Tran Hau National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Hanoi Medical University, Vietnam
  • Marco Gandolfi Unit of Dermatology, University of Parma, Parma, Italy
  • Francesca Satolli Unit of Dermatology, University of Parma, Parma, Italy
  • Claudio Feliciani Unit of Dermatology, University of Parma, Parma, Italy
  • Michael Tirant University of Rome G. Marconi, Rome, Italy; Psoriasis Eczema Clinic, Melbourne, Australia
  • Aleksandra Vojvodic Department of Dermatology and Venereology Military Medical Academy, Belgrade, Serbia
  • Torello Lotti University of Rome G. Marconi, Rome, Italy

DOI:

https://doi.org/10.3889/oamjms.2019.055

Keywords:

Phototherapy, NB-UVB, Pityriasis lichenoides chronica, Effectiveness, Safety

Abstract

AIM: This prospective clinical study presents the experiences with NB-UVB monotherapy in the treatment of PLC on Vietnamese patients.

METHODS: We enrolled at National Hospital of Dermatology and Venereology (NHDV), Vietnam, 29 PLC patients with generalised disease involving at least 60% of the total body surface (based on Nine’s Rule) and/or failed to respond to other modalities of treatment. Patients were treated with NB-UVB followed the guideline of the psoriatic treatment of AAD-2010, three times weekly.

RESULTS: A complete response (CR) was seen in 24 out of 29 PLC patients (82.8%) with a mean cumulative dose of 9760.5 mJ/cm2 after a mean treatment period of 4.6 weeks (13.8 ± 7.4 exposures). Mild side effects were observed: 69% erythema minimum, 55.2% irritation related to dry skin. No severe side effects were seen during the study. No relapses occurred in 24 CR patients within a mean period of 3 months after the last treatment.

CONCLUSION: NB-UVB therapy is an effective and safe option for the treatment and management of PLC.

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Published

2019-01-25

How to Cite

1.
Le Huu D, Ngo Minh T, Van TN, Thi Minh PP, Dinh Huu N, Cam VT, Le Huyen M, Vu Nguyet M, Le Thi M, Thi Thu HD, Tran Hau K, Gandolfi M, Satolli F, Feliciani C, Tirant M, Vojvodic A, Lotti T. The Effectiveness of Narrow Band Uvb (Nb-Uvb) In the Treatment of Pityriasis Lichenoides Chronica (PLC) In Vietnam. Open Access Maced J Med Sci [Internet]. 2019 Jan. 25 [cited 2022 May 27];7(2):221-3. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.055

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