Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis in Vietnamese Adults Patients

Authors

  • Thuong Nguyen Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
  • Ngo Hoang Thi National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Tam Hoang Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
  • Hung Le Van National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
  • Nghi Dinh Huu National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
  • Phuong Pham Thi Minh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Van Tran Cam National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • My Le Huyen National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Khang Tran Hau National Hospital of Dermatology and Venereology, Hanoi, Vietnam; Dermatology and Venerology Faculty, Hanoi Medical University, Hanoi, Vietnam
  • Marco Gandolfi Unit of Dermatology, University of Parma, Parma, Italy
  • Francesca Satolli Unit of Dermatology, University of Parma, Parma, Italy
  • Claudio Feliciani Unit of Dermatology, University of Parma, Parma, Italy
  • Michael Tirant University of Rome G. Marconi, Rome, Italy; Psoriasis Eczema Clinic, Melbourne, Australia
  • Aleksandra Vojvodic Department of Dermatology and Venereology, Military Medical Academy of Belgrade, Belgrade, Serbia
  • Torello Lotti University of Rome G. Marconi, Rome, Italy

DOI:

https://doi.org/10.3889/oamjms.2019.056

Keywords:

Seborrheic dermatitis, Oral itraconazole

Abstract

AIM: This longitudinal study aims to evaluate the efficacy of oral itraconazole in the treatment of seborrheic dermatitis in Vietnamese patients.

METHODS: Thirty patients were enrolled at National Hospital of Dermatology and Venereology, Hanoi, Vietnam and were treated with oral itraconazole (200 mg daily in 14 days followed by 200 mg weekly in 4 weeks). The clinical severity was assessed by a four-parameter scoring system. All patients completed the six-week regimen with good adherence.

RESULTS: At the week 2nd, 70% of the patients had moderate to severe diseases. At the week 6th, 63.4% of the patients achieve clearance of the lesions, and none had severe disease. No side effects were reported.

CONCLUSION: Oral itraconazole can be an option for seborrheic dermatitis because of good efficacy, safety profile and adherence.

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Published

2019-01-25

How to Cite

1.
Van TN, Hoang Thi N, Hoang Van T, Le Van H, Dinh Huu N, Thi Minh PP, Cam VT, Le Huyen M, Tran Hau K, Gandolfi M, Satolli F, Feliciani C, Tirant M, Vojvodic A, Lotti T. Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis in Vietnamese Adults Patients. Open Access Maced J Med Sci [Internet]. 2019 Jan. 25 [cited 2026 Aug. 10];7(2):224-6. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.056