Quality of Life in Psoriasis Vietnamese Patients Treated with Metformin in Combination with Methotrexate
DOI:
https://doi.org/10.3889/oamjms.2019.066Keywords:
Psoriasis, Metformin, MethotrexateAbstract
A cross-sectional study was performed on 48 psoriasis Vietnamese patients treated with metformin as an add-on for methotrexate and 48 psoriasis patients treated methotrexate alone. The mean PASI scores were 5.25 ± 5.72. Total QOL scores had a slight difference between patients treated metformin combined with methotrexate and methotrexate alone (62.32 ± 18.1 vs 60.91 ± 19.63). Combined therapy with metformin and methotrexate contributes to significantly improve the quality of life for patients with psoriasis.
Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Liang SE, Cohen JM, Ho RS. Psoriasis and suicidality: A review of the literature. Dermatologic therapy. 2018 12:e12771. https://doi.org/10.1111/dth.12771 PMid:30315629
Darjani A, Heidarzadeh A, Golchai J, Sadr-Eshkevari S, Alizadeh N, Arami M, Nichhah N. Quality of life in psoriatic patients: a study using the short form-36. International journal of preventive medicine. 2014; 5(9):1146. PMid:25317298 PMCid:PMC4192777
Damevska K, França K, Lotti T, Nikolovska S, Pollozhani N. Complementary and integrative therapies for psoriasis: Looking forward. Dermatologic therapy. 2018; 31(5):e12627. https://doi.org/10.1111/dth.12627 PMid:30133906
Glossmann H, Reider N. A marriage of two "Methusalem" drugs for the treatment of psoriasis? Arguments for a pilot trial with metformin as an add-on for methotrexate. Dermato-endocrinology. 2013; 5(2):252-63. https://doi.org/10.4161/derm.23874 PMid:24194965 PMCid:PMC3772913
Li W, Ma W, Zhong H, Liu W, Sun Q. Metformin inhibits proliferation of human keratinocytes through a mechanism associated with activation of the MAPK signalling pathway. Experimental and therapeutic medicine. 2014; 7(2):389-92. https://doi.org/10.3892/etm.2013.1416 PMid:24396411 PMCid:PMC3881035
Wollina U, França K, Lotti T, Tirant M. Adjuvant treatment of chronic plaque psoriasis in adults by a herbal combination: Open German trial and review of the literature. Dermatologic therapy. 2018 2:e12624. https://doi.org/10.1111/dth.12624 PMid:30175556
Damevska K, França K, Lotti T, Nikolovska S, Pollozhani N. Complementary and integrative therapies for psoriasis: Looking forward. Dermatologic therapy. 2018; 31(5):e12627. https://doi.org/10.1111/dth.12627 PMid:30133906
El-Gammal A, Di Nardo V, Daaboul F, Tchernev G, Wollina U, Lotti J, Lotti T. Is There a Place for Local Natural Treatment of Psoriasis? Open Access Maced J Med Sci. 2018; 6(5):839-842. https://doi.org/10.3889/oamjms.2018.106
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Tam Huynh Thi Xuan, Van Bui Thi, Anh Tran Ngoc, Em Dang Van, Quyet Tran Dang, Thuong Nguyen Van, Phuong Pham Thi Minh, Lan Pham Thi, Nghi Dinh Huu, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, Torello Lotti
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All rights reserved.
