Giant Bowen’s Disease on the Face: Case Report and Review of the Literature
DOI:
https://doi.org/10.3889/oamjms.2019.190Keywords:
Giant Bowen’s disease, dermoscopy, histopathologyAbstract
BACKGROUND: Giant Bowen’s disease is a rare and unusual clinical manifestation. Presenting as extensive scaly erythematous patch or plaque, it gives rise to a wide spectrum of dermatological differential diagnoses.
CASE PRESENTATION: We report a patient with giant Bowen’s disease on the face that was successfully treated with topical 5 % imiquimod. A review of the literature was made with the aim to analyse and compare the findings in it with our observation.
CONCLUSION: We present this case to draw attention to the importance of the self skin examination in the elderly population. Also, to prevent development to invasive squamous cell carcinoma from Bowen’s disease, we recommend mandatory dermoscopic examination on every long-standing erythemosquamous lesion.
Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Bathâ€Hextall FJ, Matin RN, Wilkinson D, et al. Interventions for cutaneous Bowen's disease. Cochrane Database of Syst Rev.2013; 6:CD007281. https://doi.org/10.1002/14651858.CD007281.pub2
Bowen JT. Precancerous dermatosis: a study of two cases of chronic atypical epithelial proliferation. J Cutan Dis Syph 1912; :241-55. In: Arch Dermatol. 1983; 119(3):243-60. https://doi.org/10.1001/archderm.1983.01650270061020 PMid:6297414
Kao GF. Carcinoma arising in Bowen's disease. Arch Dermatol 1986; 122:1124–1126. https://doi.org/10.1001/archderm.1986.01660220042010 PMid:3767398
Kallini JR, Hamed N, Khachemoune A. Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends. Int J Dermatol. 2015; 54(2):130-40. https://doi.org/10.1111/ijd.12553 PMid:25428226
Wozniak Rito AM, Rudnicka L. Bowen's disease in dermoscopy. Acta Dermatovenerol Croat 2018; 26:157-161. https://doi.org./10.2340/00015555-1328 PMid:29989873
Sotiriou E, Lallas A, Apalla Z, et al. Treatment of giant Bowen's disease with sequential use of photodynamic therapy and imiquimod cream. Photodermatology, Photoimmunology & Photomedicine. 2011; 27: 164–166. https://doi.org/10.1111/j.1600-0781.2011.00586.x PMid:21535173
Park JY, Kim SK, Cho KH, et al. Huge Bowen's disease: A pitfall of topical photodynamic therapy. Photodiagnosis and Photodyn Ther. 2013; 10(4):546-8. https://doi.org/10.1016/j.pdpdt.2013.05.001 PMid:24284109
Bakardzhiev I, Chokoeva AA, Tchernev G. Giant extragenital Bowen's disease. Wien Med Wochenschr. 2015; 165(23-24):504-7. https://doi.org/10.1007/s10354-015-0396-z PMid:26542410
Shankar AA, Pinto M, Shenoy MM, et al. Giant pigmented Bowen's disease: A rare variant at a rare site. Indian Dermatol Online J. 2015; 6:S63-4. https://doi.org/10.4103/2229-5178.171048 PMid:26904458 PMCid:PMC4738524
Baykal C, Buyukbabani N, Babuna G, et al. Giant Bowen's disease histologically showing Borst- Jadassohn phenomenon and complicated with squamous cell carcinoma development. J Eur Acad Dermatol Venerol. 2016; 30: 88-89. https://doi.org/10.1111/jdv.13335 PMid:26373350
Akay BN, Maden A, Kocak O, et al. Development of poorly differentiated invasive squamous cell carcinoma in giant Bowen's disease: a case report with dermatoscopy. Dermatol Pract Concept 2016; 6(2):2.
Nagakeerthana S, Rajesh G, Madhavi S, et al. Bowen's disease: Two case reports of a giant and dwarf lesions. J Can Res Ther. 2017; 13:371-3. https://doi.org/10.4103/0973-1482.187237 PMid:28643763
Ozlu E, Ertas R, Ozyurt K, et al. Giant neglected Bowen's disease lesion treated successfully with topical 5-fluorouracil. North Clin Istnb. 2017; 10; 4:77.
Morton CA, Whithurst C.,McColl J.H., et al. Photodynamic therapy for large or multiple patches of Bowen's disease and basal cell carcinoma. Arch Dermatol. 2001; 137: 319-324. PMid:11255332
Lopez N, Meyer-Gonzales T, Herrera-Acosta E, et al. Photodynamic therapy in the treatment of extensive Bowen's disease. J Dermatol Treat 2012; 23:428-430. https://doi.org/10.3109/09546634.2011.590789 PMid:21787214
Zalaudek I, Argenziano G, Leinweber B, et al. Dermoscopy of Bowen's disease. Br J Dermatol 2004; 150: 1112–1116. https://doi.org/10.1111/j.1365-2133.2004.05924.x PMid:15214896
Neagu TP, Tiglis M, Botezatu D. et al. Clinical, histological and therapeutic features of Bowen's disease. Rom J Morphol Embryol. 2017; 58: 33-40. PMid:28523295
Morton CA, Birnie AJ, Eedy DJ. British Association of Dermatologists' guidelines for the management of squamous cell carcinoma in situ (Bowen's disease) 2014. British Journal of Dermatology. 2014; 170: 245-260. https://doi.org/10.1111/bjd.12766 PMid:24313974
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Nina Caca-Biljanovska, Irina Arsovska-Bezhoska, Marija V’lckova-Laskoska
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
http://creativecommons.org/licenses/by-nc/4.0
