Assessment of Hyaluronic Acid Gel Injection in the Reconstruction of Interdental Papilla: A Randomized Clinical Trial

Sara Amr Abdelraouf; Omnia Aboul Dahab; Ahmed Elbarbary; Amany Mohy El-Din; Basma Mostafa Zaki

doi:10.3889/oamjms.2019.478

Authors

Sara Amr Abdelraouf Surgery and Oral Medicine Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt
Omnia Aboul Dahab Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt
Ahmed Elbarbary Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt
Amany Mohy El-Din Surgery and Oral Medicine Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt
Basma Mostafa Zaki Assistant Professor of Oral Medicine and Periodontology, Surgery and Oral Medicine Department, Oral and Dental Research Division, National Research Centre, Cairo, Egypt http://orcid.org/0000-0001-7246-9666

DOI:

https://doi.org/10.3889/oamjms.2019.478

Keywords:

Deficient interdental papilla, Reconstruction, Hyaluronic acid, Injection

Abstract

BACKGROUND: Various techniques have been implemented to reconstruct the deficient interdental papilla.
AIM: The present trial was conducted to assess the effect of injection of hyaluronic acid gel for the reconstruction of deficient interdental papilla.
MATERIAL AND METHODS: Thirty-six deficient interdental papilla sites in ten patients were randomly allocated into two equal groups; intervention group who received the injection of hyaluronic acid (HA) gel and control group who received the injection of saline solution as a placebo. Each deficient papilla received three injections. The first injection was given one week following the re-evaluation period (four weeks after performing full mouth supra-gingival scaling and sub-gingival debridement). The second and third injections were given after three and six weeks, respectively. The height and surface area of black triangles were recorded at baseline before the injection procedures. The participants were recalled after three and six months from the first injection for re-measuring the recorded parameters. At 6 months, patients' satisfaction was also assessed.
RESULTS: After three and six months from baseline, the results revealed a statistically significant higher mean decrease in height and surface area of black triangles in favour of the HA group. From three to six months, there was no statistically significant difference between the two groups in both parameters. At 6 months, the HA group showed a statistically significant higher mean satisfaction score than the saline group.
CONCLUSION: The use of hyaluronic acid gel for the reconstruction of interdental papillary deficiency was effective with promising levels of patients' satisfaction.