Comparative Effectiveness Study of Chloramphenicol and Ceftriaxone in the Treatment of Typhoid Fever in Children Admitted to Putri Hijau Kesdam I/Bb Hospital Medan
DOI:
https://doi.org/10.3889/oamjms.2019.517Keywords:
Chloramphenicol, Ceftriaxone, Typhoid Fever, Cost EffectivenessAbstract
BACKGROUND: Typhoid fever is a disease caused by Salmonella typhi bacteria, especially attacking the digestive tract. Chloramphenicol is the main drug of choice for the treatment of typhoid fever. But along with the advancement of the medical field, other medicines were developed. Ceftriaxone is an effective drug for the treatment of typhoid fever in the short term. But the price of ceftriaxone is more expensive.
AIM: The aim of this study was comparative effectiveness study of Chloramphenicol and Ceftriaxone in the treatment of typhoid fever in children admitted to Putri Hijau Kesdam I/BB Hospital Medan
METHODS: This study was conducted cross-sectionally about the treatment of typhoid fever in children who were hospitalized at TK II PutriHijau Hospital Kesdam I/BB Medan. the patient used cloramfenikol antibiotics in 13 patients and used ceftriaxone in 17 patients. Patient age ranges from 0-19 years. Antibiotic analysis is the best effectiveness using the ACER method.
RESULTS: He results of the patient characteristics show that the children of patients who suffer from typhoid fever, the highest age is 12-16 years (50%), by gender male 60% and female 40%. Patients hospitalized using chloramfenicol averaged 6.53 days (7 days) while ceftriaxon averaged 4.17 days. The average number of direct medical costs in pediatric patients suffering from typhoid fever using cloramfenikol was 3,212,776/patient while ceftriaxon 1,967,045/patient. Cost effectiveness analysis using ACER method obtained results for cloramenicenicol at 492.002/day and ceftriaxon 471,713/day
CONCLUSION: Ceftriaxone has a better treatment effectiveness compared to chloramphenicol in typhoid fever patients in children.
Downloads
Metrics
Plum Analytics Artifact Widget Block
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Eva Sartika Dasopang, Fenny Hasanah, Teddy Kurniawan Bakri, Muktia Isma (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
http://creativecommons.org/licenses/by-nc/4.0