Oral Hard Tissue Lesions: A Radiographic Diagnostic Decision Tree

Authors

  • Hamed Mortazavi Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Yaser Safi Department of Oral and Maxillofacial Radiology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Somayeh Rahmani Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Kosar Rezaeifar Department of Oral Medicine, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

DOI:

https://doi.org/10.3889/oamjms.2020.4722

Keywords:

Radiolucent, Radiopaque, Maxilla, Mandible, Odontogenic, Nonodontogenic

Abstract

BACKGROUND: Focusing on history taking and an analytical approach to patient’s radiographs, help to narrow the differential diagnoses.

AIM: This narrative review article aimed to introduce an updated radiographical diagnostic decision tree for oral hard tissue lesions according to their radiographic features.

METHODS: General search engines and specialized databases including PubMed, PubMed Central, Scopus, Embase, EBSCO, ScienceDirect, and authenticated textbooks were used to find relevant topics by means of MeSH keywords such as “jaw diseases,” “maxilla,” “mandible,” “radiolucent,” “radiopaque,” “odontogenic,” “nonodontogenic,” “cysts,” and “tumors.” Related English-language articles published from 1973 to 2020, including reviews, meta-analyses, and original papers (randomized or non-randomized clinical trials; prospective; or retrospective cohort studies), case reports, and case series about oral hard tissue lesions were appraised.

RESULTS: In this regard, bony lesions have been classified according to their radiographic pattern (radiolucent, mixed, radiopaque, and rarified), position (periapical, pericoronal and interradicular), margins (well and ill-defined), relation to dentition (with and without dental association), and number (solitary and multiple). In total, 50 entities were organized in the form of a decision tree.

CONCLUSION: In this paper, an updated decision tree was proposed to help dental practitioners to make more accurate diagnoses and better treatment plans on the basis of radiographic characteristics.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Plum Analytics Artifact Widget Block

References

Mortazavi H, Baharvand M, Rahmani S, Jafari S, Parvaei P. Radiolucent rim as a possible diagnostic aid for differentiating jaw lesions. Imaging Sci Dent. 2015;45(4):253-61. https://doi. org/10.5624/isd.2015.45.4.253 PMid:26730374

Neyaz Z, Gadodia A, Gamanagatti S, Mukhopadhyay S. Radiographical approach to jaw lesions. Singapore Med J. 2008;49(2):165-77.

George G, Padiyath S. Unicystic jaw lesions: A radiographic guideline. J Indian Acad Oral Med Radiol. 2010;22:S31-6. https://doi.org/10.5005/jp-journals-10011-1065

Mortazavi H, Baharvand M, Safi Y, Behnaz M. Common conditions associated with displacement of the inferior alveolar nerve canal: A radiographic diagnostic aid. Imaging Sci Dent. 2019;49(2):79-86. https://doi.org/10.5624/isd.2019.49.2.79 PMid:31281784

Narula H, Ahuja B, Yeluri R, Baliga S, Munshi AK. Conservative non-surgical management of an infected radicular cyst. Contemp Clin Dent. 2011;2(4):368-71. https://doi. org/10.4103/0976-237x.91806 PMid:22346170

Shah AA, Sangle A, Bussari S, Koshy AV. Glandular odontogenic cyst: A diagnostic dilemma. Indian J Dent. 2016;7(1):38-43. https://doi.org/10.4103/0975-962x.179371 PMid:27134453

Ferreira JC, Vêncio EF, de Sá RT, Gasperini G. Glandular odontogenic cyst in dentigerous relationship: An uncommon case report. Case Rep Dent. 2019;2019:8647158. https://doi. org/10.1155/2019/8647158 PMid:31355014

Ahmad A, Tadinada A. Evaluation of incisive canal cysts: 2-D vs 3-D imaging. Have we learnt anything new? Oral Surg Oral Med Oral Pathol Oral Radiol. 2019;128(4):e163. https://doi. org/10.1016/j.oooo.2019.01.034

Dedhia P, Dedhia S, Dhokar A, Desai A. Nasopalatine duct cyst. Case Rep Dent. 2013;2013:869516. https://doi. org/10.1155/2013/869516 PMid:24307954

Bhandari R, Sandhu SV, Bansal H, Behl R, Bhullar RK. Focal cemento-osseous dysplasia masquerading as a residual cyst. Contemp Clin Dent. 2012;3 Suppl 1:S60-2. https://doi. org/10.4103/0976-237x.95107 PMid:22629069

Roghi M, Scapparone C, Crippa R, Silvestrini-Biavati A, Angiero F. Periapical cemento-osseous dysplasia: Clinico pathological features. Anticancer Res. 2014;34(5):2533-6. PMid:24778071

Brody A, Zalatnai A, Csomo K, Belik A, Dobo-Nagy C. Difficulties in the diagnosis of periapical translucencies and in the classification of cemento-osseous dysplasia. BMC Oral Health. 2019;19(1):139. https://doi.org/10.1186/s12903-019-0843-0 PMid:31291935

Sridevi K, Nandan SR, Ratnakar P, Srikrishna K, Pavani BV. Residual cyst associated with calcifications in an elderly patient. J Clin Diagn Res. 2014;8(2):246-9. PMid:24701547

Wood NK, Goaz PW. Differential Diagnosis of Oral and Maxillofacial Lesions. 5th ed. St Louis: Mosby-Year Book Inc.; 1997.

Wang Y, Le A, El Demellawy D, Shago M, Odell M, Johnson- Obaseki S. An aggressive central giant cell granuloma in a pediatric patient: Case report and review of literature. J Otolaryngol Head Neck Surg. 2019;48(1):32. https://doi. org/10.1186/s40463-019-0356-5 PMid:31319877

Alves DB, Tuji FM, Alves FA, Rocha AC, Santos-Silva AR, Vargas PA, et al. Evaluation of mandibular odontogenic keratocyst and ameloblastoma by panoramic radiograph and computed tomography. Dentomaxillofac Radiol. 2018;47(7):20170288. https://doi.org/10.1259/dmfr.20170288 PMid:29791200

Mortazavi H, Baharvand M. Jaw lesions associated with impacted tooth: A radiographic diagnostic guide. Imaging Sci Dent. 2016;46(3):147-57. https://doi.org/10.5624/isd.2016.46.3.147 PMid:27672610

Borghesi A, Nardi C, Giannitto C, Tironi A, Maroldi R, Di Bartolomeo F, et al. Odontogenic keratocyst: Imaging features of a benign lesion with an aggressive behaviour. Insights Imaging. 2018;9(5):883-97. https://doi.org/10.1007/s13244-018-0644-z PMid:30066143

Shokri A, Baharvand M, Mortazavi H. Is cone-beam computed tomography diagnostic for anterior Stafne bone cyst: Report of a rare case? Dent Hypotheses. 2015;6(1):31-3. https://doi. org/10.4103/2155-8213.150872

Lee JI, Kang SJ, Jeon SP, Sun H. Stafne bone cavity of the mandible. Arch Craniofac Surg. 2016;17(3):162-4. https://doi. org/10.7181/acfs.2016.17.3.162 PMid:28913275

Kumar LK, Kurien N, Thaha KA. Traumatic bone cyst of mandible. J Maxillofac Oral Surg. 2015;14(2):466-9. https://doi. org/10.1007/s12663-010-0114-8 PMid:26028875

Razmara F, Ghoncheh Z, Shabankare G. Traumatic bone cyst of mandible: A case series. J Med Case Rep. 2019;13(1):300. https://doi.org/10.1186/s13256-019-2220-7 PMid:31530284

Papadaki ME, Lietman SA, Levine MA, Olsen BR, Kaban LB, Reichenberger EJ. Cherubism: Best clinical practice. Orphanet J Rare Dis. 2012;7 Suppl 1:S6. https://doi. org/10.1186/1750-1172-7-s1-s6 PMid:22640403

Das BK, Das SN, Gupta A, Nayak S. Florid cemento-osseous dysplasia. J Oral Maxillofac Pathol. 2013;17(1):150. https://doi. org/10.4103/0973-029x.110735 PMid:23798858

Daviet-Noual V, Ejeil AL, Gossiome C, Moreau N, Salmon B. Differentiating early stage florid osseous dysplasia from periapical endodontic lesions: A radiological-based diagnostic algorithm. BMC Oral Health. 2017;17(1):161. https://doi. org/10.1186/s12903-017-0455-5 PMid:29284472

Nangalia R, Chatterjee RP, Kundu S, Pal M. Langerhans cell histiocytosis in an adult with oral cavity involvement: Posing a diagnostic challenge. Contemp Clin Dent. 2019;10(1):154-7. https://doi.org/10.4103/ccd.ccd_432_18 PMid:32015659

Islinger RB, Kuklo TR, Owens BD, Horan PJ, Choma TJ, Murphey MD, et al. Langerhans’ cell histiocytosis in patients older than 21 years. Clin Orthop Relat Res. 2000;379:231-5. https://doi.org/10.1097/00003086-200010000-00027 PMid:11039811

Ida-Yonemochi H, Tanabe Y, Ono Y, Murata M, Saku T. Focal osteoporotic bone marrow defects associated with a cystic change of the maxilla: A possible histopathogenetic background of simple bone cyst. Oral Med Pathol. 2010;15:35-8. https://doi. org/10.3353/omp.15.35

Simancas-pallares M, Arevalo-tovat L, Marincola M. Focal osteoporotic bone marrow defects on dental implant treated patients: A 5-year period prevalence study. Int J Odontostomatol. 2016;10(1):23-8. https://doi.org/10.4067/ s0718-381x2016000100005

Ramalingam S, Alrayyes YF, Almutairi KB, Bello IO. Lateral periodontal cyst treated with enucleation and guided bone regeneration: A report of a case and a review of pertinent literature. Case Rep Dent. 2019;2019:4591019. https://doi. org/10.1155/2019/4591019

Meseli SE, Agrali OB, Peker O, Kuru L. Treatment of lateral periodontal cyst with guided tissue regeneration. Eur J Dent. 2014;8(3):419-23. https://doi.org/10.4103/1305-7456.137661 PMid:25202227

Vasudevan K, Kumar S, Vijayasamundeeswari, Vigneswari S. Adenomatoid odontogenic tumor, an uncommon tumor. Contemp Clin Dent. 2012;3(2):245-7. https://doi. org/10.4103/0976-237x.96837 PMid:22919236

Chrcanovic BR, Gomez RS. Adenomatoid odontogenic tumor: An updated analysis of the cases reported in the literature. J Oral Pathol Med. 2019;48(1):10-6. https://doi.org/10.1111/ jop.12783 PMid:30256456

Demiriz L, Misir AF, Gorur DI. Dentigerous cyst in a young child. Eur J Dent. 2015;9(4):599-602. https://doi. org/10.4103/1305-7456.172619 PMid:26929702

Ghandour L, Bahmad HF, Bou-Assi S. Conservative treatment of dentigerous cyst by marsupialization in a young female patient: A case report and review of the literature. Case Rep Dent. 2018;2018(2):7621363. https://doi.org/10.1155/2018/7621363

Agani Z, Hamiti-Krasniqi V, Recica J, Loxha MP, Kurshumliu F, Rexhepi A. Maxillary unicystic ameloblastoma: A case report. BMC Res Notes. 2016;9(1):469. https://doi.org/10.1186/ s13104-016-2260-7 PMid:27756334

Carroll C, Gill M, Bowden E, O’Connell JE, Shukla R, Sweet C. Ameloblastic fibroma of the mandible reconstructed with autogenous parietal bone: Report of a case and literature review. Case Rep Dent. 2019;2019:5149219. https://doi. org/10.1155/2019/5149219

Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO. Ameloblastoma: Current etiopathological concepts and management. Oral Dis. 2018;24(3):307-16. https://doi. org/10.1111/odi.12646 PMid:28142213

Devi P, Thimmarasa V, Mehrotra V, Agarwal M. Aneurysmal bone cyst of the mandible: A case report and review of literature. J Oral Maxillofac Pathol. 2011;15(1):105-8. https://doi. org/10.4103/0973-029x.80014 PMid:21731290

Dereci O, Acikalin MF, Ay S. Unusual intraosseous capillary hemangioma of the mandible. Eur J Dent. 2015;9(3):438-41. https://doi.org/10.4103/1305-7456.163236 PMid:26430377

Dhiman NK, Jaiswara C, Kumar N, Patne SC, Pandey A, Verma V. Central cavernous hemangioma of mandible: Case report and review of literature. Natl J Maxillofac Surg. 2015;6(2):209-13. https://doi.org/10.4103/0975-5950.183866 PMid:27390499

Mortazavi H, Baharvand M, Safi Y, Dalaie K, Behnaz M, Safari F. Common conditions associated with mandibular canal widening: A literature review. Imaging Sci Dent. 2019;49(2):87-95. https:// doi.org/10.5624/isd.2019.49.2.87 PMid:31281785

Gupta S, Grover N, Kadam A, Gupta S, Sah K, Sunitha JD. Odontogenic myxoma. Natl J Maxillofac Surg. 2013;4(1):81-3. https://doi.org/10.4103/0975-5950.117879 PMid:24163558

Shivashankara C, Nidoni M, Patil S, Shashikala KT. Odontogenic myxoma: A review with report of an uncommon case with recurrence in the mandible of a teenage male. Saudi Dent J. 2017;29(3):93-101. https://doi.org/10.1016/j.sdentj.2017.02.003 PMid:28725126

Deshmukh R, Joshi S, Deo PN. Nonfamilial cherubism: A case report and review of literature. J Oral Maxillofac Pathol. 2017;21(1):181. https://doi.org/10.4103/0973-029x.203791 PMid:28479714

Mortazavi H, Baharvand M. Review of common conditions associated with periodontal ligament widening. Imaging Sci Dent. 2016;46(4):229-37. https://doi.org/10.5624/isd.2016.46.4.229 PMid:28035300

Sammartino G, Marenzi G, Howard CM, Minimo C, Trosino O, Califano L, et al. Chondrosarcoma of the jaw: A closer look at its management. J Oral Maxillofac Surg. 2008;66(11):2349-55. https://doi.org/10.1016/j.joms.2006.05.069 PMid:18940505

Margaix-Muñoz M, Bagán J, Poveda-Roda R. Ewing sarcoma of the oral cavity. A review. J Clin Exp Dent. 2017;9(2):e294-301. https://doi.org/10.4317/jced.53575 PMid:28210452

Casaroto AR, DA Silva Sampieri MB, Soares CT, DA Silva Santos PS, Yaedu RY, Damante JH, et al. Ewing’s sarcoma family tumors in the jaws: Case report, immunohistochemical analysis and literature review. In Vivo. 2017;31(3):481-91. https://doi.org/10.21873/invivo.11087 PMid:28438883

Yang HY, Su BC, Hwang MJ, Lee YP. Fibrous dysplasia of the anterior mandible: A rare case report. Ci Ji Yi Xue Za Zhi. 2018;30(3):185-7. https://doi.org/10.4103/tcmj.tcmj_57_18 PMid:30069129

Ogunsalu C, Smith NJ, Lewis A. Fibrous dysplasia of the jaw bone: A review of 15 new cases and two cases of recurrence in Jamaica together with a case report. Aust Dent J. 1998;43(6):390-4. https://doi.org/10.1111/j.1834-7819.1998. tb00198.x PMid:9973707

Gudmundsson T, Torkov P, Thygesen T. Diagnosis and treatment of osteomyelitis of the jaw-a systematic review (2002-2015) of the literature. J Dent Oral Disord. 2017;3(4):1066.

Koorbusch GF, Deatherage JR, CuréJK. How can we diagnose and treat osteomyelitis of the jaws as early as possible? Oral Maxillofac Surg Clin North Am. 2011;23(4):557-67. https://doi. org/10.1016/j.coms.2011.07.011 PMid:21982609

Babazade F, Mortazavi H, Jalalian H. Bilateral metachronous osteosarcoma of the mandibular body: A case report. Chang Gung Med J. 2011;34 Suppl 6:66-9. PMid:22490463

Sengupta S, Vij H, Vij R. Primary intraosseous carcinoma of the mandible: A report of two cases. J Oral Maxillofac Pathol. 2010;14(2):69-72. https://doi.org/10.4103/0973-029x.72504 PMid:21731266

Thomas G, Pandey M, Mathew A, Abraham EK, Francis A, Somanathan T, et al. Primary intraosseous carcinoma of the jaw: Pooled analysis of world literature and report of two new cases. Int J Oral Maxillofac Surg. 2001;30(4):349-55. https://doi. org/10.1054/ijom.2001.0069 PMid:11518362

Garg B, Chavada R, Pandey R, Gupta A. Cementoblastoma associated with the primary second molar: An unusual case report. J Oral Maxillofac Pathol. 2019;23 Suppl 1:111-4. https:// doi.org/10.4103/jomfp.jomfp_83_18 PMid:30967738

Borges DC, Rogério de Faria P, Júnior HM, Pereira LB. Conservative treatment of a periapical cementoblastoma: A case report. J Oral Maxillofac Surg. 2019;77(2):272.e1-7. https://doi.org/10.1016/j.joms.2018.10.003 PMid:30414393

Holly D, Jurkovic R, Mracna J. Condensing osteitis in oral region. Bratisl Lek Listy. 2009;110(11):713-5. PMid:20120441

Farhadi F, Ruhani MR, Zarandi A. Frequency and pattern of idiopathic osteosclerosis and condensing osteitis lesions in panoramic radiography of Iranian patients. Dent Res J (Isfahan). 2016;13(4):322-6. https://doi.org/10.4103/1735-3327.187880 PMid:27605989

Pinto AS, Carvalho MS, de Farias AL, da Silva Firmino B, da Silva Dias LP, Neto JM, et al. Hypercementosis: Diagnostic imaging by radiograph, cone-beam computed tomography, and magnetic resonance imaging. J Oral Maxillofac Radiol. 2017;5(3):90-3. https://doi.org/10.4103/jomr.jomr_27_17

Mortazavi H, Parvaie P. Multiple hypercementosis: Report of a rare presentation. J Dent Mater Tech. 2016;5(3):158-60. Available from: http://www.jdmt.mums.ac.ir/article_6872.html. https://doi.org/10.22038/JDMT.2016.6872

Santos HB, de Morais EF, Moreira DG, Neto LF, Gomes PP, Freitas RA. Calcifying odontogenic cyst with extensive areas of dentinoid: Uncommon case report and update of main findings. Case Rep Pathol. 2018;2018:8323215. https://doi. org/10.1155/2018/8323215 PMid:29862107

Ram R, Singhal A, Singhal P. Cemento-ossifying fibroma. Contemp Clin Dent. 2012;3(1):83-5. https://doi. org/10.4103/0976-237x.94553 PMid:22557904

Tolentino ES, Gusmão PH, Cardia GS, Tolentino LS, Iwaki LC, Amoroso-Silva PA. Idiopathic osteosclerosis of the jaw in a Brazilian population: A retrospective study. Acta Stomatol Croat. 2014;48(3):183-92. https://doi.org/10.15644/asc48/3/2 PMid:27688365

Kumar G, Manjunatha B. Metastatic tumors to the jaws and oral cavity. J Oral Maxillofac Pathol. 2013;17(1):71-5. https://doi. org/10.4103/0973-029x.110737 PMid:23798834

Hirshberg A, Berger R, Allon I, Kaplan I. Metastatic tumors to the jaws and mouth. Head Neck Pathol. 2014;8(4):463-74. https:// doi.org/10.1007/s12105-014-0591-z PMid:25409855

Kaur H, Verma S, Jawanda MK, Sharma A. Aggressive osteoblastoma of the mandible: A diagnostic dilemma. Dent Res J (Isfahan). 2012;9(3):334-7. PMid:23087741

Sahu S, Padhiary S, Banerjee R, Ghosh S. Osteoblastoma of mandible: A unique entity. Contemp Clin Dent. 2019;10(2):402-5. PMid:32308310

Khaitan T, Ramaswamy P, Ginjupally U, Kabiraj A. A bizarre presentation of osteoid osteoma of maxilla. Iran J Pathol. 2016;11(5):431-4. PMid:28974960

Karandikar S, Thakur G, Tijare M, Shreenivas K, Agrawal K. Osteoid osteoma of mandible. BMJ Case Rep. 2011;2011:bcr1020114886. https://doi.org/10.1136/ bcr.10.2011.4886 PMid:22669768

Burrell KH, Goepp RA. Abnormal bone repair in jaws, socket sclerosis: A sign of systemic disease. J Am Dent Assoc. 1973;87(6):1206-15. https://doi.org/10.14219/jada. archive.1973.0556 PMid:4521580

Khurana NA, Khurana G, Uppal N. Socket sclerosis, a rare complication in orthodontic tooth movement. Contemp Clin Dent. 2010;1(4):255-8. PMid:22114433

Jayachandran S, Vasudevi R, Kayal L. Atypical presentation of Paget’s disease with secondary osteomyelitis of mandible. J Indian Acad Oral Med Radiol. 2017;29(3):227-30. https://doi. org/10.4103/jiaomr.jiaomr_54_17

Karunakaran K, Murugesan P, Rajeshwar G, Babu S. Paget’s disease of the mandible. J Oral Maxillofac Pathol. 2012;16(1):107-9. https://doi.org/10.4103/0973-029x.92984 PMid:22434946

Piva CG, Miyagaki DC, Linden MS, de Conto F, Rinaldi I, de Carli J. Ameloblastic fibro-odontoma: Case report. RGO Rev Gaúcha Odontol. 2017;65(3):265-9. https://doi. org/10.1590/1981-863720170002000133222

Kumar LK, Manuel S, Khalam SA, Venugopal K, Sivakumar TT, Issac J. Ameloblastic fibro-odontoma. Int J Surg Case Rep. 2014;5(12):1142-4. https://doi.org/10.1016/j.ijscr.2014.11.025 PMid:25437658

Cankaya B, İşler SC, Gümüşdal A, Genç B, Asadov C. Unusual location of calcifying epithelial odontogenic tumor. J Oral Maxillofac Radiol. 2019;7(2):44-8. https://doi.org/10.4103/jomr. jomr_18_19

Fazeli SR, Giglou KR, Soliman ML, Ezzat WH, Salama A, Zhao Q. Calcifying epithelial odontogenic (pindborg) tumor in a child: A case report and literature review. Head Neck Pathol. 2019;13(4):580-6. https://doi.org/10.1007/s12105-019-01009-1 PMid:30771214

Prabhu N, Issrani R, Patil S, Srinivasan A, Alam MK. Odontoma-an unfolding enigma. J Int Oral Health. 2019;11:334-9. https://doi. org/10.4103/jioh.jioh_115_19

Gedik R, Müftüoğlu S. Compound odontoma: Differential diagnosis and review of the literature. West Indian Med J. 2014;63(7):793-5. https://doi.org/10.7727/wimj.2013.272 PMid:25867569

Aerden T, Grisar K, Nys M, Politis C. Secondary hyperparathyroidism causing increased jaw bone density and mandibular pain: A case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;125(3):e37-41. https://doi.org/10.1016/j. oooo.2017.11.020 PMid:29310888

Mittal S, Gupta D, Sekhri S, Goyal S. Oral manifestations of parathyroid disorders and its dental management. J Dent Allied Sci. 2014;3(1):34-8. https://doi.org/10.4103/2277-4696.156527

Gulsahi A. Osteoporosis and jawbones in women. J Int Soc Prev Community Dent. 2015;5(4):263-7. PMid:26312225

Wankhede AN, Sayed AJ, Gattani DR, Bhutada GP. Periodontitis associated with osteomalacia. J Indian Soc Periodontol. 2014;18(5):637-40. https://doi.org/10.4103/0972-124x.142461 PMid:25425827

Downloads

Published

2020-08-25

How to Cite

1.
Mortazavi H, Safi Y, Rahmani S, Rezaeifar K. Oral Hard Tissue Lesions: A Radiographic Diagnostic Decision Tree. Open Access Maced J Med Sci [Internet]. 2020 Aug. 25 [cited 2024 Nov. 21];8(F):180-96. Available from: https://oamjms.eu/index.php/mjms/article/view/4722

Issue

Section

Narrative Review Article

Categories