A Dermoscopic Evaluation of Melasma Treated with Tranexamic Acid

O T B. Sarah; Abeer Attia Tawfik; Mona Soliman; Eman Shaarawy; Noha Abdallah

doi:10.3889/oamjms.2022.7429

Authors

O T B. Sarah PHD Studies, Cairo University, Giza, Egypt
Abeer Attia Tawfik Department of Medical Application of Laser
Mona Soliman Department of Medical Application of Laser, Dermatology Unit, National Institute of Laser and Enhanced Sciences, Cairo University, Giza, Egypt
Eman Shaarawy Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt
Noha Abdallah Department of Medical Application of Laser, Dermatology Unit, National Institute of Laser and Enhanced Sciences, Cairo University, Giza, Egypt

DOI:

https://doi.org/10.3889/oamjms.2022.7429

Keywords:

Melasma, Dermoscopy, MASI, Tranexamic acid

Abstract

Background:

Melasma is a great challenge to the dermatologist. Choosing the proper treatment and the evaluation method are hard issues. Tranexamic acid [TA] injections showed promising results. The dermoscope is a non -invasive hand held tool

Objective:

To evaluate the efficacy of TA injections in the management of melasma and to assess a new dermoscopic score for assessment of melasma severity.

Patients & Methods:

Twenty-seven patients were enrolled in the study. They were assessed clinically, and by dermoscopy. An intradermal tranexamic acid was injected on the melasma. Melasma Area and Severity Index [MASI] was used to assess the melasma.

Results: high significant difference was found between pre [4.700±2.1213] and post [2.811±2.0870] treatment values of MASI score [p= 0.0001]. Clinically TA treatment showed a dramatic improvement in MASI.

Conclusion:

The intradermal usage of TA can actually decrease improved the melasma. This was confirmed by the MASI scores and the dermoscope. The dermoscope could be considered as a useful objective score for melasma.

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