Anosmia in COVID-19 Patients at a Health Center in Yogyakarta, Indonesia

Authors

  • Rizka Fakhriani Department of Otorhinolaryngology-Head-and-Neck Surgery, Faculty of Medicine and Health Science, Universitas Muhammadiyah, Yogyakarta, Indonesia https://orcid.org/0000-0002-8373-5293
  • Asti Widuri Department of Otorhinolaryngology-Head-and-Neck Surgery, Faculty of Medicine and Health Science, Universitas Muhammadiyah, Yogyakarta, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.8944

Keywords:

COVID-19, Anosmia, Olfactory function

Abstract

BACKGROUND: SARS-CoV-2, which causes COVID-19, is one of the viruses that has been spreading globally since 2019.

AIM: This research aims to see how common anosmia is among COVID-19 patients.

MATERIALS AND METHODS: A retrospective study with a consecutive sample and quantitative descriptive design was utilized to collect data by spreading questionnaires on patient experiences COVID-19 infection. COVID-19 was detected by RT-PCR at a Health Center in Yogyakarta, Indonesia.

RESULT: A total of 124 persons tested positive for COVID-19. The remaining 59% experienced no anosmia or smell issues. Anosmia was present in 40.3% of those examined, 57.3% of those tested had no anosmia before or after the RT-PCR test and 31.5 had it before being diagnosed with COVID-19. Less than 5 days, 13.7% of those who had recovered, whereas 22.6% had more than 5 days to recover.

CONCLUSION: People who were diagnosed as COVID-19 positive using the RT-PCR test had the symptom earlier than those who reported anosmia after diagnosis, according to when they first reported it.

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References

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-33. https://doi.org/10.1056/NEJMoa2001017 PMid:31978945 DOI: https://doi.org/10.1056/NEJMoa2001017

Astuti I, Ysrafil Y. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response. Diabetes Metab Syndr. 2020;14(4):407-12. https://doi.org/10.1016/j.dsx.2020.04.020 PMid:32335367 DOI: https://doi.org/10.1016/j.dsx.2020.04.020

Meng X, Deng, Y, Dai Z, Meng Z. COVID-19 and anosmia: A review based on up-to-date knowledge. Am J Otolaryngol. 2020;41(5):102581. https://doi.org/10.1016/j.amjoto.2020.102581 PMid:32563019 DOI: https://doi.org/10.1016/j.amjoto.2020.102581

Carrillo-Larco RM, Altez-Fernandez C. Anosmia and dysgeusia in COVID-19: A systematic review. Wellcome Open Res. 2020;5:94. https://doi.org/10.12688/wellcomeopenres.15917.1 PMid:32587902 DOI: https://doi.org/10.12688/wellcomeopenres.15917.1

Kulaga HM, Leitch CC, Eichers ER, Badano JL, Lesemann A, Hoskins BE, et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat Genet. 2004;36(9):994-8. https://doi.org/10.1038/ng1418 PMid:15322545 DOI: https://doi.org/10.1038/ng1418

Li X, Lui F. Anosmia. Treasure Island (FL): StatPearls; 2019.

Lüers JC, Klußmann JP, Guntinas-Lichius O. The COVID-19 pandemic and otolaryngology: What it comes down to? Laryngorhinootologie. 2020;99(5):287-291. https://doi.org/10.1055/a-1095-2344 PMid:32215896 DOI: https://doi.org/10.1055/a-1095-2344

Mao L, Jin H, Wang M, Yu H, Chen S, He Q, et al. Neurologic manifestations of hospitalized patients with Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683-90. https://doi.org/10.1001/jamaneurol.2020.1127 PMid:32275288 DOI: https://doi.org/10.1001/jamaneurol.2020.1127

Tanasa IA, Manciuc C, Carauleanu A, Navolan DB, Bohiltea RE, Nemescu D. Anosmia and ageusia associated with coronavirus infection (COVID-19) - what is known? Exp Ther Med. 2020;20(3):2344-7. https://doi.org/10.3892/etm.2020.8808 PMid:32765712 DOI: https://doi.org/10.3892/etm.2020.8808

Krajewska J, Krajewski W, Zub K, Zatoński T. COVID-19 in otolaryngologist practice: A review of current knowledge. Eur Arch Otorhinolaryngol. 2020;277(7):1885-97. https://doi.org/10.1007/s00405-020-05968-y PMid:32306118 DOI: https://doi.org/10.1007/s00405-020-05968-y

Cherry G, Rocke J, Chu M, Liu J, Lechner M, Lund VJ, et al. Loss of smell and taste: A new marker of COVID-19? Tracking reduced sense of smell during the coronavirus pandemic using search trends. Expert Rev Anti Infect Ther. 2020;18(11):1165-70. DOI: https://doi.org/10.1080/14787210.2020.1792289

Saniasiaya J, Islam MA, Abdullah B. Prevalence of olfactory dysfunction in coronavirus disease 2019 (COVID‐19): A meta‐analysis of 27,492 patients. Laryngoscope. 2020;131(4):865-78. https://doi.org/10.1002/lary.29286 PMid:33219539 DOI: https://doi.org/10.1002/lary.29286

Finsterer J, Stollberger C. Causes of hypogeusia/hyposmia in SARS‐CoV2 infected patients. J Med Virol. 2020;92(10):1793-4. https://doi.org/10.1002/jmv.25903 PMid:32311107 DOI: https://doi.org/10.1002/jmv.25903

Barón-Sánchez J, Santiago C, Martín G, Arca R, Fernández R. Smell and taste disorders in Spanish patients with mild COVID-19. Neurología (Engl Ed). 2020;35(9):633-8. https://doi.org/10.1016/j.nrleng.2020.07.007 PMid:32900532 DOI: https://doi.org/10.1016/j.nrleng.2020.07.007

Hariyanto TI, Rizki NA, Kurniawan A. Anosmia/hyposmia is a good predictor of coronavirus disease 2019 (COVID-19) infection: A meta-analysis. Int Arch Otorhinolaryngol. 2020;25(1):e170-4. https://doi.org/10.1055/s-0040-1719120 PMid:33552295 DOI: https://doi.org/10.1055/s-0040-1719120

Klopfenstein T, Kadiane-Oussou NJ, Toko L, Royer PY, Lepiller Q, Gendrin V, et al. Features of anosmia in COVID-19. Méd Mal Infect. 2020;50(5):436-9. https://doi.org/10.1016/j.medmal.2020.04.006 PMid:32305563 DOI: https://doi.org/10.1016/j.medmal.2020.04.006

Uddin M, Mustafa F, Rizvi TA, Loney T, Suwaidi HA, Al-Marzouqi AH, et al. SARS-CoV-2/COVID-19: Viral genomics, epidemiology, vaccines, and therapeutic interventions. Viruses. 2020;12(5):526. https://doi.org/10.3390/v12050526 PMid:32397688 DOI: https://doi.org/10.3390/v12050526

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. https://doi.org/10.1016/S0140-6736(20)30183-5 PMid:31986264 DOI: https://doi.org/10.1016/S0140-6736(20)30183-5

Damm M, Pikart LK, Reimann H, Burkert S, Göktas Ö, Haxel B, et al. Olfactory training is helpful in postinfectious olfactory loss: A randomized, controlled, multicenter study. Laryngoscope. 2014;124(4):826-31. PMid:23929687 DOI: https://doi.org/10.1002/lary.24340

Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A, et al. Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): A multicenter European study. Eur Arch Otorhinolaryngol. 2020;277(8): https://doi.org/10.1007/s00405-020-05965-1 PMid:32253535 DOI: https://doi.org/10.1007/s00405-020-05965-1

Stenner M, Vent J, Hüttenbrink KB, Hummel T, Damm M. Topical therapy in anosmia: Relevance of steroid‐responsiveness. Laryngoscope. 2008;118(9):1681-6. https://doi.org/10.1097/MLG.0b013e31817c1368 PMid:18677278 DOI: https://doi.org/10.1097/MLG.0b013e31817c1368

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Published

2022-05-06

How to Cite

1.
Fakhriani R, Widuri A. Anosmia in COVID-19 Patients at a Health Center in Yogyakarta, Indonesia. Open Access Maced J Med Sci [Internet]. 2022 May 6 [cited 2024 Apr. 26];10(G):517-20. Available from: https://oamjms.eu/index.php/mjms/article/view/8944

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Nursing in Internal Medicine

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