Association between Nephrolithiasis, Hypertension and Obesity in Polycystic Kidney Disease
Keywords:nephrolithiasis, hypertension, polycystic kidney disease, body mass index, anatomic and metabolic factors
AIM: We aim to define the correlations between nephrolithiasis, hypertension, age and obesity in patients with autosomal dominant polycystic kidney disease (ADPKD) in Albania.
MATERIAL AND METHODS: We included 100 patients with autosomal dominant polycystic kidney from 2011 to 2014. The patients underwent X-ray and renal ultrasonography. We performed the metabolic evaluation of blood and urine.
RESULTS: The patients with renal stones had a higher level of mean systolic and diastolic blood pressure compared with patients without stones (155 Â± 12 mmHg vs. 145 Â± 8 mmHg, and 105 Â± 0.9 mmHg vs. 92 Â± 1.28 mmHg, respectively). Patients with renal stones were older (47 Â± 15 vs. 38 Â± 5 years), had a higher prevalence of obesity [body mass index (BMI): 28 Â± 2.4 vs. 25.7 Â± 0.6], had higher levels of total cholesterol level (220 Â± 5 mg/dl vs. 203 Â± 4 mg/dl) as well as triglyceride levels (160 Â± 9 mg/dl vs. 126 Â± 4 mg/dl), compared with no renal stone individuals.CONCLUSION: ADPKD patients with renal stones in our study had a higher mean level of systolic and diastolic blood pressure, BMI and cholesterol and triglycerides levels compared with individuals without renal stones.
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