The Predictive Role of Procalcitonin On the Treatment of Intra-Abdominal Infections

Dafina Mahmutaj; Shaip Krasniqi; Bedri Braha; Dalip Limani; Burim Neziri

doi:10.3889/oamjms.2017.194

Authors

Dafina Mahmutaj Clinic of Surgery, University Clinical Center of Kosovo, Hospital and University Clinical Service of Kosovo, Prishtina, Kosovo
Shaip Krasniqi Faculty of Medicine, University of Prishtina â€œHasan Prishtinaâ€, Prishtina, Kosovo
Bedri Braha Clinic of Surgery, University Clinical Center of Kosovo, Hospital and University Clinical Service of Kosovo, Prishtina, Kosovo
Dalip Limani Clinic of Surgery, University Clinical Center of Kosovo, Hospital and University Clinical Service of Kosovo, Prishtina, Kosovo
Burim Neziri Faculty of Medicine, University of Prishtina â€œHasan Prishtinaâ€, Prishtina, Kosovo

DOI:

https://doi.org/10.3889/oamjms.2017.194

Keywords:

intraabdominal infections, procalcitonin, antibiotic, microbiological examination, CRP

Abstract

Aim: This study aims to evaluate the algorithm of procalcitonin (PCT) and its role on the duration of antibiotics prescription for intra-abdominal infections.

Materials and Methods: This study is a prospective controlled study that is conducted in groups of 50 hospitalised patients and 50 controlled group patients.

Results: The results indicated that the average duration of antibiotic delivery to the PCT group was -10.6 days (SD Â± 6.6 days), while in the control group -13.2 days (SD Â± 4.2 days). These data showed a significant difference in the duration of antibiotic therapy and the monitoring role of PCTs in the prediction success of antibiotic treatment. The antibiotic delivery was longer in the septic shock 17 (SD Â± 11.7) that corresponds to high PCT values of 67.8 (SD Â± 50.9). Recurrence of the infection after the cessation of antibiotics occurred in 2 cases (4%) in the standard group, while it occurred in 3 cases (6%) in the control group.

Conclusion: The treatment of the intra-abdominal infections based on the PCT algorithm shortens the duration of antibiotic treatment and does not pose a risk for the recurrence of the infection.

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