Real World Experience of a Biodegradable Polymer Sirolimus-Eluting Stent (Yukon Choice PC Elite) in Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Angioplasty: A Multicentric Observational Study (The Elite India Study)


  • Bhupendra Verma Department of Cardiology, Ujala Superspeciality Hospital, Kashipur, Uttarakhand, India
  • Akhilesh Patel Abhigya Heart Care Centre, Gorakhpur, Uttar Pradesh, India
  • Deepak Katyal Department of Cardiology, Columbia Asia Hospital, Patiala, Punjab, India
  • Vivek Raj Singh Vardhan Heart Clinic, Varanasi, Uttar Pradesh, India
  • Avinash Kumar Singh Department of Cardiology, Khushlok Hospital, Bareilly, Uttar Pradesh, India
  • Amrita Singh Department of Cardiology, Ujala Superspeciality Hospital, Kashipur, Uttarakhand, India
  • Manu Kumar Department of Cardiology, Ujala Superspeciality Hospital, Kashipur, Uttarakhand, India
  • Pratap Nagarkoti Department of Cardiology, Ujala Superspeciality Hospital, Kashipur, Uttarakhand, India



BPDES, STEMI, Percutaneous coronary intervention, Third generation stents, Drug-eluting stents, Deliverability, Stent thrombosis


BACKGROUND: The durable polymer drug-eluting stents (DPDES) reduce the risk of repeated target vessel revascularisation (TLR) compared with BMS, but are associated with increased risk of late adverse events. In broadly inclusive populations, the biodegradable-polymer drug-eluting stents (BPDES) have favourable results compared with DPDES in the long term. However, its use in primary angioplasty has not been adequately studied, and data of real-world clinical experience is lacking.

AIM: Aim of this study was to assess the safety and efficacy of Yukon Choice PC Elite sirolimus-eluting stent (a novel BPDES) in STEMI patients undergoing primary angioplasty.

METHODS: We have presented here one-year clinical follow-up data of the Yukon Choice PC Elite sirolimus-eluting stent in patients undergoing primary angioplasty. A total of 636 patients were enrolled in this single arm, prospective observational study from five centres.

RESULTS: This multicentric observational study showed excellent safety and efficacy profile of the novel device at one year follow up. The device-oriented composite endpoint (DOCE) of cardiac death, target-vessel reinfarction, and target-lesion revascularisation (TLR) was 2.7%, and the patient-oriented composite endpoint (POCE) of all-cause death, any myocardial infarction, and any revascularisation was 4.2% at one year. Definite or probable stent thrombosis rate was 0.6%, and no events were recorded beyond 6 months of follow up.

CONCLUSIONS: In patients with STEMI undergoing primary angioplasty, the use of Yukon Choice PC Elite (biodegradable polymer sirolimus-eluting stent) has excellent results at one year. It, therefore, represents an attractive alternative to second generation DES in this high-risk population.


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How to Cite

Verma B, Patel A, Katyal D, Singh VR, Singh AK, Singh A, Kumar M, Nagarkoti P. Real World Experience of a Biodegradable Polymer Sirolimus-Eluting Stent (Yukon Choice PC Elite) in Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Angioplasty: A Multicentric Observational Study (The Elite India Study). Open Access Maced J Med Sci [Internet]. 2019 Apr. 13 [cited 2024 Jun. 17];7(7):1103-9. Available from:



B - Clinical Sciences