Physical Evaluation and Anti-Aging Effect of Red Bean Ethanolic Extract (Vigna angularis (Wild.) Ohwi & Ohashi) Peel-Off Gel Mask

Authors

  • Bayu Eko Prasetyo Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia; Nanomedicine Center of Innovation, Universitas Sumatera Utara, Medan, 20155, Indonesia
  • Dwi Rafika Faculty of Pharmacy, Tjut Nyak Dhien University, Medan, Indonesia
  • Lia Laila Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia
  • Fat Aminah Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, 20155, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2019.531

Keywords:

Peel-off Mask, Gel, Red bean, Anti-aging

Abstract

BACKGROUND: The product development of an anti-aging dosage for human skin is a very interesting issue because every human wants to be looked young as long as possible. A studies and development of plant that contain of antioxidant properties need to be studied further.

AIM: The aim of this research was to formulate and evaluate the physical and anti-aging effect of the Peel-Off Gel Mask from Red Bean Ethanol Extract (PGMRB).

METHODS: The Extract Ethanol of Red Bean was extracted by maceration methods with ethanol 96%. The Peel-off base was consisted of Polyvinyl alcohol, glycerin and carbomer 940. The gel formulation was made in 3 formulas (F1, F2, and F3) consisted with 1%, 3% and 5% ethanol extract, respectively. The blank formula (F0) was also prepared as a control formula. The evaluation of gel formulation included organoleptic test, pH determination, stability test, homogeneity test, peeling time, irritation test and anti-aging effect test included moisture level, skin pore size, the evenness test and dark spot test by using skin analyzer.

RESULTS: All of the formula showed a homogen, pH around 6, peeling time less than 20 minutes, no irritation and stable for 12 weeks storage at room temperature. The treatment with PGMRB demonstrated an improvement on the moisture level, pore size, evenness and the number of black spots with F3 containing 5% extract as the best formula.

CONCLUSION: The ethanol extract of red bean can be formulated become a peel-off gel mask and having the anti-aging effect.

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Published

2019-11-14

How to Cite

1.
Prasetyo BE, Rafika D, Laila L, Aminah F. Physical Evaluation and Anti-Aging Effect of Red Bean Ethanolic Extract (Vigna angularis (Wild.) Ohwi & Ohashi) Peel-Off Gel Mask. Open Access Maced J Med Sci [Internet]. 2019 Nov. 14 [cited 2024 Apr. 19];7(22):3907-10. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.531

Issue

Section

Herbal Medicine in Pharmaceutical and Clinical Sciences