Impetiginized Dyshidrotic Eczema


  • Georgi Tchernev Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, and Onkoderma Polyclinic for Dermatology and Dermatologic Surgery, Sofia
  • Matteo Zanardelli Pharmacology, Toxicology and Innovative Treatments, Rome
  • Cristiana Voicu Dermatology Department, Polisano Clinic, 26Z Timisoara Blvd, Bucharest
  • Ilko Bakardzhiev Medical College, Medical University of Varna, Varna 9000
  • Torello Lotti Department of Dermatology, University of Rome “G. Marconi”; Rome, Italy; Department of Biotechnology, Delft University of Technology, 2628 BC, Delft
  • Jacopo Lotti Department of Nuclear, Subnuclear and Radiation Physics, University of Rome "G. Marconi", Rome
  • Katlein França Institute for Bioethics & Health Policy; Department of Dermatology & Cutaneous Surgery; Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine - Miami, FL
  • Atanas Batashki Abdominal and Thoracic Surgery, Department of Special Surgery, Medical University of Plovdiv, bul. "Peshtersko shose" Nr 66, 4000, Plovdiv
  • Uwe Wollina Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067, Dresden



hand dermatitis, superinfections, St. aureus, clobetasol, skin barrier


A 16 years old female patient, affected by atopic dermatitis and rhinoconjunctivitis allergica since childhood, requested a dermatologic consultation for lesions which had appeared after 3 months of local treatment with clobethasole propionate. The histological analysis confirmed the diagnosis of dyshidrotic eczema and the microbiological smears demonstrated a significant infection with Staphylococcus aureus. The risk of developing corticosteroids’ side-effects depends on the potency of the product, extended period of use and the volume of product applied. Clobetasol propionate is a group I- highly potent corticosteroid, which should be used for a maximum period of 2 weeks. Several authors have found that this agent has cumulative depot effect, persisting in the epidermis for 4 days after only one application. Taking together these observations, sustained by the clinical case presented above, we can conclude that the infectious risks associated with topical corticosteroid treatment must not be neglected, particularly since treated patients are fragile, and frequently have multiple well-known risk factors.


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How to Cite

Tchernev G, Zanardelli M, Voicu C, Bakardzhiev I, Lotti T, Lotti J, França K, Batashki A, Wollina U. Impetiginized Dyshidrotic Eczema. Open Access Maced J Med Sci [Internet]. 2017 Jul. 19 [cited 2023 Sep. 27];5(4):539-40. Available from:

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