Very Rare Amelanotic Lentigo Maligna Melanoma with Skull Roof Invasion

Authors

  • Uwe Wollina Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
  • Gesina Hansel Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
  • Nadine Schmidt Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt in Dresden, Dresden
  • Jacqueline Schönlebe Städtisches Klinikum Dresden - Institute of Pathology "Georg Schmorl", Dresden
  • Thomas Kittner Stadtisches Klinikum Dresden, Department of Radiology, Dresden, Sachsen
  • Andreas Nowak Department of Anesthesiology & Intensive Care Medicine, Emergency Medicine & Pain Management, Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, Friedrichstrasse 41, 01067, Dresden

DOI:

https://doi.org/10.3889/oamjms.2017.113

Keywords:

Melanoma, amelanotic lentigo malignant melanoma, relapses, surgery, skull invasion, follow-up

Abstract

BACKGROUND: Lentigo malignant melanoma is a melanoma subtype of chronic sun-damaged skin in elderly Caucasians. Amelanotic variants of lentigo malignant are extremely rare.

CASE PRESENTATION: This is a case report of an 80-year-old male patient who presented with a non-pigmented exophytic tumour of his bald head. After complete surgical excision under the suspicion of squamous cell carcinoma, three-dimensional histologic examination confirmed an amelanotic lentigo malignant melanoma with a tumour thickness of 1.76 mm, resected R0. Five years later he developed the first relapse, the other year a satellite metastasis was surgically removed. One year later, this patient had developed a large relapsing lentigo malignant melanoma with skull roof invasion. There was no evidence of distant metastatic spread. Amelanotic lentigo malignant melanoma is a very rare tumour.

CONCLUSIONS: Serial excision or slow Mohs and Mohs micrographic surgery are the treatments of choice especially in the head and neck area. These tumours may be locally very aggressive as it is shown by skull invasion in the present case.

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References

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Published

2017-07-19

How to Cite

1.
Wollina U, Hansel G, Schmidt N, Schönlebe J, Kittner T, Nowak A. Very Rare Amelanotic Lentigo Maligna Melanoma with Skull Roof Invasion. Open Access Maced J Med Sci [Internet]. 2017 Jul. 19 [cited 2023 Feb. 4];5(4):458-61. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.113

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