Hoigne Syndrome Caused by Intralesional Meglumine Antimoniate


  • Claudio Guarneri Universita degli Studi di Messina, Clinical and Experimental Medicine, Section of Dermatology, Messina 98122
  • Georgi Tchernev Medical Institute of the Ministry of Interior, Dermatology, Venereology and Dermatologic Surgery; Onkoderma, Private Clinic for Dermatologic Surgery, Dermatology and Surgery, Sofia 1407
  • Uwe Wollina Krankenhaus Dresden-Friedrichstadt, Department of Dermatology and Venereology, Dresden, Sachsen
  • Torello Lotti Universitario di Ruolo, Dipartimento di Scienze Dermatologiche, Università degli Studi di Firenze, Facoltà di Medicina e Chirurgia, Dermatology, Via Vittoria Colonna 11, Rome 00186




Hoigne syndrome, adverse drug reaction, injection, meglumine antimoniate, leishmaniasis


Hoigne syndrome (HS) is the term coined to describe an acute, non-allergic, psychiatrically based reaction occurring with a wide list of medications, mainly antibiotics. Since its first description by Hoigne and Schoch in 1959, few cases have been reported in medical literature and, although antimicrobials are commonly used, very rarely in dermatology. The authors describe the first case occurred after intralesional administration of meglumine antimoniate and briefly discuss the pathogenetic hypotheses on this atypical adverse drug reaction.


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How to Cite

Guarneri C, Tchernev G, Wollina U, Lotti T. Hoigne Syndrome Caused by Intralesional Meglumine Antimoniate. Open Access Maced J Med Sci [Internet]. 2017 Jul. 22 [cited 2023 Dec. 6];5(4):483-5. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.136

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