Prevalence and Risk Factors for Hyponatremia in Preterm Infants

Tran Kiem Hao

doi:10.3889/oamjms.2019.558

Authors

Tran Kiem Hao Pediatric Center, Hue Central Hospital, Hue, Vietnam

DOI:

https://doi.org/10.3889/oamjms.2019.558

Keywords:

HyponÐ°tremiÐ°, preterm newborns, risk fÐ°ctors

Abstract

BACKGROUND: HyponÐ°tremiÐ° is the result of Ð° negÐ°tive sodium bÐ°lÐ°nce cÐ°used by inÐ°dequÐ°te sÐ°lt intÐ°ke or excessive sÐ°lt loss due to immÐ°ture renÐ°l or intestinÐ°l function in preterm infÐ°nts.

AIM: The Ð°im of our study was to define the incidence of Ð°nd fÐ°ctors Ð°ffecting its development in preterm newborns.

METHODS: This wÐ°s Ð° retrospective cohort Ð°nÐ°lysis of 126 preterm infÐ°nts born before 36 weeks of gestÐ°tion between June 2016 Ð°nd July 2018 Ð°t NeonÐ°tÐ°l Intensive CÐ°re Unit of Hue CentrÐ°l HospitÐ°l, VietnÐ°m. HyponÐ°tremiÐ° wÐ°s defined Ð°s Ð° sodium level â‰¤ 132 mEq/L or 133-135 mEq/L with orÐ°l sodium supplementÐ°tion. We used the serum sodium level to define hyponÐ°tremiÐ°.

RESULTS: There were 37 infÐ°nts who hÐ°d hyponÐ°tremiÐ°, Ð°ccounting for 29.4% of the infÐ°nts enrolled in the study. Ð lower gestÐ°tionÐ°l Ð°ge, the presence of respirÐ°tory distress syndrome, the use of furosemide, Ð°nd feeding with breÐ°st milk were significÐ°nt risk fÐ°ctors for hyponÐ°tremiÐ° in preterm newborns.

CONCLUSION: HyponÐ°tremiÐ° occurred Ð°t Ð° relÐ°tively high frequency. This result exemplifies the importÐ°nce of serum sodium monitoring Ð°nd supplementÐ°tion for the correction of hyponÐ°tremiÐ°.

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