Wells Syndrome â€“ An Odyssey

Birgit Heinig; Aleksandra Vojvodic; Torello Lotti; Michael Tirant; Uwe Wollina

doi:10.3889/oamjms.2019.572

Authors

Birgit Heinig Center of Physical and Rehabilitative Medicine, StÃ¤dtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany
Aleksandra Vojvodic Military Medical Academy of Belgrade, Belgrade, Serbia
Torello Lotti Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome, Italy
Michael Tirant Department of Dermatology, University of Rome â€œG. Marconiâ€, Rome, Italy
Uwe Wollina Department of Dermatology and Allergology, StÃ¤dtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany

DOI:

https://doi.org/10.3889/oamjms.2019.572

Keywords:

Eosinophilic skin diseases, Wells syndrome, Flame figure, Eosinophila, Treatment, Interleukin-5

Abstract

BACKGROUND: Wells syndrome is a rare idiopathic dermatosis of the eosinophilic spectrum. Diagnostic criteria include cutaneous eruptions of variable morphology with eosinophilic infiltrates, peripheral blood eosinophilia, a relapsing, remitting course, and exclusion of systemic disease. Diagnosis is often delayed.

CASE PRESENTATION: We present a 28-year older man with recently developed pruritic and sometimes painful erythema. His medical history was positive for coughing in the evening that started in November 2012. Later, a pansinusitis developed. Early diagnosis improves the outcome.

CONCLUSION: Standardized treatment has yet to be developed. In our case, systemic corticosteroids were of limited value only.