Correlation between Soil-Transmitted Helminths Infection and Serum Iron Level among Primary School Children in Medan

Authors

  • Nurfida Khairina Arrasyid Parasitology Department, Faculty of Medicine, University of Sumatera Utara, Medan
  • Monica Nadya Sinambela Faculty of Medicine, University of Sumatera Utara, Medan
  • Zaimah Z. Tala Nutrition Department, Faculty of Medicine, University of Sumatera Utara, Medan
  • Dewi Masyithah Darlan University of Sumatera Utara
  • Syah Mirsya Warli Urology Department, Faculty of Medicine, University of Sumatera Utara, Medan

DOI:

https://doi.org/10.3889/oamjms.2017.016

Keywords:

soil-transmitted helminths, serum iron, primary school, Medan

Abstract

BACKGROUND: The latest estimates indicate that more than 2 billion people worldwide are infected by Soil-Transmitted Helminths (STH). The burden of STH infection is mainly attributed to the chronic effect on health and quality of life of those infected. It is also contributed to micronutrient deficiencies such as iron-deficiency anaemia. The prevalence of worm infection in Public Primary School students in Medan was quite high (40.3%), and 33.3% was anaemic in the latest study.

AIM: To determine the correlation between STH infection with serum iron (SI) level on primary school children, as well as to determine the prevalence of SI level and worm infection, and the type of worm that infects the most of them.

METHODS: This study was conducted in the cross-sectional method. Consecutive sampling technique was used and a total of 132 students age 8-12 years old were included. The study took places in Public Primary School 060925 Amplas, Medan and 101747 Hamparan Perak, Deli Serdang throughout May-October 2016. Fisher Exact test was used to analyse the correlation between STH infection and SI level.

RESULTS: The prevalence of STH infection was 7.6%, and low SI was 11.4%.

CONCLUSION: There was no significant correlation between STH infection and SI level (P = 0.317). The prevalence of low SI level was not significantly dependent on STH infection (RP = 1.877, 95% CI = 0.481-7.181).

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Author Biographies

Nurfida Khairina Arrasyid, Parasitology Department, Faculty of Medicine, University of Sumatera Utara, Medan

Parasitology Department

Monica Nadya Sinambela, Faculty of Medicine, University of Sumatera Utara, Medan

Medical Student

Dewi Masyithah Darlan, University of Sumatera Utara

Parasitology Department, Faculty of Medicine

References

World Health Organization. Soil Transmitted Helminthiases: eliminating soil transmitted helminthiases as a public health problem in children: progress report 2001-2010. Geneva: World Health Organization, 2012.

Prichard RK, Basá-ez MG, Boatin BA, McCarthy JS, García HH, Yang GJ, et al. A Research Agenda for Helminth Diseases of Humans: Intervention for Control and Elimination. PLoS Negl Trop Dis. 2012; 6(4):e1549: 1-14. DOI: https://doi.org/10.1371/journal.pntd.0001549

Ziegelbauer K, Speich B, Mausezahl D, Bos R, Keiser J, Utzinger J. Effect of Sanitation on Soil-Transmitted Helminth Infection: Systematic Review and Meta-Analysis. PLoS Med. 2012; 9(1):e1001162: 1-17. DOI: https://doi.org/10.1371/journal.pmed.1001162

Lustigman S, Prichard RK, Gazzinelli A, Grant WN, Boatin BA, McCarthy JS, et al. A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases. PLoS Negl Trop Dis. 2012; 6(4):e1582: 1-13 DOI: https://doi.org/10.1371/journal.pntd.0001582

Dewi Masyithah Darlan, Ferry FV Kaban. Correlation between Soil Transmitted Helminth Infection and Incidence of Anemia at Public Primary School 060925. International Journal of PharmTech Research. 2016; 9(6):185-190.

Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006; 367(9521): 1521-32. https://doi.org/10.1016/S0140-6736(06)68653-4 DOI: https://doi.org/10.1016/S0140-6736(06)68653-4

Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. J Clin Invest. 2008; 118:1311–21. https://doi.org/10.1172/JCI34261 PMid:18382743 PMCid:PMC2276811 DOI: https://doi.org/10.1172/JCI34261

Kaminsky RG, Ault SK, Castillo P, Serrano K, Troya G. High prevalence of soil-transmitted helminths in Southern Belize highlighting opportunity for Control interventions. Asian Pac J Trop Biomed. 2014; 4(5): 345-53. https://doi.org/10.12980/APJTB.4.201414B3 PMid:25182717 PMCid:PMC3985047 DOI: https://doi.org/10.12980/APJTB.4.201414B3

World Health Organization. Worldwide prevalence of anaemia 1993-2015. Spain: World Health Organization, 2008.

Özdemir N. Iron deficiency anemia from diagnosis to treatment in children. Türk Ped Arş. 2015; 50: 11-9. https://doi.org/10.5152/tpa.2015.2337 PMid:26078692 PMCid:PMC4462328 DOI: https://doi.org/10.5152/tpa.2015.2337

Barkley JS, Kendrick KL, Codling K, Muslimatun S, Pachón H. Anaemia prevalence over time in Indonesia: estimates from the 1997, 2000, and 2008 Indonesia Family Life Surveys. Asia Pac J Clin Nutr. 2015; 24(3): 452-55. PMid:26420186

Mujib ASM, Mahmud ASM, Halder M, Hasan CMM. Study of Hematological Parameters in Children Suffering from Iron Deficiency Anaemia in Chattagram Maa-o-Shishu General Hospital, Chittagong, Bangladesh. Anemia. 2014; Article ID 503981: 1-10. DOI: https://doi.org/10.1155/2014/503981

World Health Organization. Iron Deficiency Anaemia Assessment, Prevention, and Control. Geneva: World Health Organization, 2001.

Aini UN, Al-Mekhlafi MSH, Azlin M, Shaik A, Sa'iah A, Fatmah MS, et al. Serum iron status in Orang Asli children living in endemic areas of soil transmitted helminthes. Asia Pac J Clin Nutr. 2007; 16(4): 724-30. PMid:18042535

Ngui R, Lim YA, Kin LC, Chuen CS, Jaffar S. Association between anaemia, iron deficiency anaemia, neglected parasitic infections and socioeconomic factors in rural children of West Malaysia. PLoS Negl Trop Dis. 2012;6(3):e1550. https://doi.org/10.1371/journal.pntd.0001550 PMid:22413027 PMCid:PMC3295806

Arinola GO, Morenikeji OA, Akinwande KS, Alade AO, Olagbegi OO, Alabi PE, et al. Serum Micronutrients in Helminth-infected Pregnant Women and Children: Suggestions for Differential Supplementation During Antihelminthic Treatment. Ann Global Health. 2015; 81(5): 705-10. https://doi.org/10.1016/j.aogh.2015.10.001 PMid:27036729 DOI: https://doi.org/10.1016/j.aogh.2015.10.001

Ciesla B. Hematology in Practice: The Microcytic Anemias. United States of America: F.A. Davis Company, 2007.

Factors in Rural Children of West Malaysia. PLoS Negl Trop Dis. 2012; 6(3): e1550: 1-8. DOI: https://doi.org/10.1371/journal.pntd.0001550

Published

2017-03-19

How to Cite

1.
Arrasyid NK, Sinambela MN, Tala ZZ, Darlan DM, Warli SM. Correlation between Soil-Transmitted Helminths Infection and Serum Iron Level among Primary School Children in Medan. Open Access Maced J Med Sci [Internet]. 2017 Mar. 19 [cited 2024 Apr. 19];5(2):117-20. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2017.016

Issue

Section

A - Basic Science

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