Multiple Primary Acral Lentiginous Melanomas (MPALM)
DOI:
https://doi.org/10.3889/oamjms.2017.162Keywords:
melanoma, multiple primary tumours, acral located tumours, amputations, stagingAbstract
We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolated from current literature; however, that appropriate management of these patients, including staging work and surgical intervention, is to be determined by the individual characteristics of the melanoma and the patient's concomitant risk factors, if any.Downloads
Metrics
Plum Analytics Artifact Widget Block
References
Asgari MM, Shen L, Sokil MM, Yeh I, Jorgenson E. Prognostics factors and survival in acral lentiginous melanoma. Br J Dermatol. 2017 Apr 22. https://doi.org/10.1111/bjd.15600 DOI: https://doi.org/10.1111/bjd.15600
Kuchelmeister C, Schaumburg-Lever G, Garbe C. Acral cutaneous melanoma in Caucasians: clinical features, histopathology and prognosis in 112 patients. Br J Dermatol. 2000; 143(2):275-80. https://doi.org/10.1046/j.1365-2133.2000.03651.x PMid:10951133 DOI: https://doi.org/10.1046/j.1365-2133.2000.03651.x
Bradford PT, Goldstein AM, McMaster ML, Tucker MA. Acral lentiginous melanoma: incidence and survival patterns in the United States, 1986-2005. Arch Dermatol. 2009; 145(4):427-34. https://doi.org/10.1001/archdermatol.2008.609 PMid:19380664 PMCid:PMC2735055 DOI: https://doi.org/10.1001/archdermatol.2008.609
Nam KW, Bae YC, Nam SB, Kim JH, Kim HS, Choi YJ.Characteristics and Treatment of Cutaneous Melanoma of the Foot. Arch Plast Surg. 2016; 43(1):59-65. https://doi.org/10.5999/aps.2016.43.1.59 PMid:26848447 PMCid:PMC4738130 DOI: https://doi.org/10.5999/aps.2016.43.1.59
Hayes AJ, Clark MA, Harries M, Thomas JM. Management of in-transit metastases from cutaneous malignant melanoma. Br J Surg. 2004; 91(6):673-82. https://doi.org/10.1002/bjs.4610 PMid:15164434 DOI: https://doi.org/10.1002/bjs.4610
Lacruz G, Cárdenas I, Carrera C, DÃaz A, Puig-Butillè JA, Badenas C, Malvehy J, Puig S. Multiple primary acral melanomas in two young caucasian patients. Dermatology. 2014;228(4):307-10. https://doi.org/10.1159/000362207 PMid:24942556 DOI: https://doi.org/10.1159/000362207
Hutcheson AC, McGowan JW 4th, Maize JC Jr, Cook J. Multiple primary acral melanomas in African-Americans: a case series and review of the literature. Dermatol Surg. 2007;33(1):1-10. https://doi.org/10.1097/00042728-200701000-00001 DOI: https://doi.org/10.1111/j.1524-4725.2007.33000.x
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Miriam González, Georgi Tchernev, Anastasiya Atanasova–Chokoeva, Katlein França, Torello Lotti (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
