Differences in Hemoglobin Levels in Pregnant Women through Multi-Micronutrient Supplements and Iron Tablets

Authors

  • Jamaludin Sakung Department of Health Biochemistry, Faculty of Teacher Training and Education, Tadulako University, Palu, Indonesia
  • Dewi Tosae Department of Midwifery, STIKES Guna Bangsa Yogyakarta, Depok, Indonesia
  • Gunarmi Gunarmi Department of Midwifery, STIKES Guna Bangsa Yogyakarta, Depok, Indonesia
  • Andi Imam Arundhana Department of Nutrition, School of Public Health, Hasanuddin University, Makassar, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2022.7794

Keywords:

Anemia, Multi-micronutrient, Pregnant women, Low-middle-income countries

Abstract

BACKGROUND: A high incidence of anemia, particularly severe anemia, among pregnant women has been a major cause of maternal mortality worldwide. Multi-micronutrient supplement (MMS) has been beneficial for health outcomes.

AIM: The study was aimed to examine the effect of MMS compared to iron-folic acid supplement (IFA) on hemoglobin (Hb) levels among pregnant women.

METHODS: The study was a quasi-experiment with a three-group pre-post-test design, namely, IFA group, MMS group, and MMS + IFA group. A total of 120 participants enrolled were divided equally in each group. The statistical analysis performed was paired t-test and one-way ANOVA using SPSS.

RESULTS: The study result shows that there was a significant difference in the Hb levels of pregnant women after the intervention in all groups (p < 0.001). The highest increase in Hb levels was in the IFA + MMS combining group by 1.1 g/dL of Hb followed by MMS and IFA (0.8 ± 0.37 and 0.4 ± 0.31, respectively).

CONCLUSION: The combination of Fe and MMS groups could increase Hb levels compared to IFA. Thus, replacing IFA with MMS is reasonably in preventing anemia among pregnant women.

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References

Ilmi IM, Arini FA, Novriyanti D. Torbangun leaf snack bar: An alternative source for iron and calcium for breastfeeding mothers in post-disaster refugee camp. Indones J Nutr Sci. 2021;1(1):157. DOI: https://doi.org/10.52023/ijns.v1i1.2516

Siti I, Siahaan S, Wanggae G, Widyasari R, Kurniawan A, Aryastami NK, Pratiwi NL. dinamika jender terhadap akses pelayanan kesehatan maternal sembilan etnis di Indonesia. Bulet Penelitian Sistem Kesehatan. 2019;22(1):1-9. DOI: https://doi.org/10.22435/hsr.v22i1.439

Tarigan DF, Andriani F. Hubungan paritas dengan kejadian retensio plasenta di rumah sakit umum daerah H. Abdul manan simatupang kisaran kabupaten asahan tahun 2019. J Gentle Birth. 2020;3(1):12-8. DOI: https://doi.org/10.36082/qjk.v12i2.38

Pamungkas CE, Amini A. Refreshing penyuluhan tanda-tanda bahaya kehamilan menggunakan buku kia pada kelas ibu hamil di wilayah kerja puskesmas karang Pule. J Pengabdian Masyarakat Kebidanan. 2020;2(1):23-30. DOI: https://doi.org/10.31764/mj.v2i2.805

Sakung JM, Sirajuddin S, Zulkifli A, Rahman SA, Palutturi S. The effect of chayote (sechium edule) on blood glucose level of high school teachers of pre-diabetes. Executive Editor. 2018;9(5):245. DOI: https://doi.org/10.5958/0976-5506.2018.00447.3

Lee JE, Lee J, Lee H, Park JK, Park Y, Choi WS. End‐of‐life care needs for noncancer patients who want to die at home in South Korea. Int J Nurs Pract 2020;26(2):e12808. https://doi.org/10.1111/ijn.12808 PMid:31975562 DOI: https://doi.org/10.1111/ijn.12808

Mirza FG, Abdul-Kadir R, Breymann C, Fraser IS, Taher A. Impact and management of iron deficiency and iron deficiency anemia in women’s health. Expert Rev Hematolol. 2018;119:727-36. https://doi.org/10.1080/17474086.2018.1502081 PMid:30019973 DOI: https://doi.org/10.1080/17474086.2018.1502081

Dziembowska I, Kwapisz J, Izdebski P, Żekanowska E. Mild iron deficiency may affect female endurance and behavior. Physiol Behav. 2019;205:44-50. DOI: https://doi.org/10.1016/j.physbeh.2018.09.012

Accinelli RA, Leon-Abarca JA. Age and altitude of residence determine anemia prevalence in Peruvian 6 to 35 months old children. PLoS One. 2020;15(1):e0226846. https://doi.org/10.1371/journal.pone.0226846 PMid:31940318 DOI: https://doi.org/10.1371/journal.pone.0226846

Alam F, Khanum S, Jahan I, Ahmed JU. Prevalence and sociodemographic factors responsible for anaemia in pregnancy: Experience in a military hospital in Bangladesh. BIRDEM Med J. 2021;11(1):52-6. DOI: https://doi.org/10.3329/birdem.v11i1.51030

Gammage S, Sultana N, Glinski A. Reducing vulnerable employment: Is there a role for reproductive health, social protection, and labor market policy? Feminist Econ. 2020;26(1):121-53. DOI: https://doi.org/10.1080/13545701.2019.1670350

Hurley K, Achadi EL, Ajello C, Askari S, Bajoria M, Beesabathuni K, et al. Prevention of child wasting in Asia: Possible role for multiple micronutrient supplementation in pregnancy. Field Exchange 2020;63:76.

Horino M, Bahar M, Al-Jawaldeh A, Seita A, Hurley K, Kraemer K, et al. Antenatal multiple micronutrient supplementation in the state of palestine: A protocol for implementation and evaluation. Curr Dev Nutr. 2021;5(2):1316-6. DOI: https://doi.org/10.1093/cdn/nzab059_017

Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet. 2016;387(10021):907-16. https://doi.org/10.1016/S0140-6736(15)60865-0 DOI: https://doi.org/10.1016/S0140-6736(15)60865-0

Handayani KD, Widyawati MN. The effect of combination alkaline water and iron tablets on improving hemoglobin level among adolescent. Int J Nurs Health Serv. 2020;3(5):615-21.

Sari AP. The Effectiveness of Iron Tablets Consumption in Pregnant Women to Ferritin Levels in Ilir Timur I Palembang. Netherlands: Atlantis Press; 2021. p. 5-8.

Gulo NS, Anuhgerah DE, Handayani D. Efektivitas tablet zat besi terhadap perubahan tekanan darah ibu hamil. J Kebidanan Kestra. 2021;3(2):149-57. DOI: https://doi.org/10.35451/jkk.v3i2.675

Zehra A, Abdullah SM, Saboor M. Effect of intravenous iron supplementation on hepcidin levels in iron deficient pregnant females in second and third trimester. Indian J Hematol Blood Transf. 2017;33(3):396-401. https://doi.org/10.1007/s12288-016-0736-1 PMid:28824243 DOI: https://doi.org/10.1007/s12288-016-0736-1

Donahue Angel M, Berti P, Siekmans K, Tugirimana PL, Boy E. Prevalence of iron deficiency and iron deficiency anemia in the northern and southern provinces of Rwanda. Food Nutr Bull. 2017;38(4):554-63. https://doi.org/10.1177/0379572117723134 PMid:28826251 DOI: https://doi.org/10.1177/0379572117723134

Hasswane N, Bouziane A, Mrabet M, Laamiri FZ, Aguenaou H, Barkat A. Prevalence and factors associated with anemia pregnancy in a group of Moroccan pregnant women. J Biosci Med. 2015;3(10):88. DOI: https://doi.org/10.4236/jbm.2015.310012

Skania PC, Dasuki D, Utami FS. The effect of fe tablet consumption on hemoglobin (Hb) increase in pregnant women: A systematic literature review. J Kebidanan Midwiferia. 2020;6(2):8-13. DOI: https://doi.org/10.21070/midwiferia.v6i2.568

Smith ER, Shankar AH, Wu LS, Aboud S, Adu-Afarwuah S, Ali H, et al. Modifiers of the effect of maternal multiple micronutrient supplementation on stillbirth, birth outcomes, and infant mortality: A meta-analysis of individual patient data from 17 randomised trials in low-income and middle-income countries. Lancet Global Health. 2017;5(11):e1090-100. https://doi.org/10.1016/S2214-109X(17)30371-6 PMid:29025632 DOI: https://doi.org/10.1016/S2214-109X(17)30371-6

Hepi Gita K. Hubungan Tingkat Konsumsi Protein, Zat Besi dan Kadar Hemoglobin dengan Produktivitas Kerja Tenaga Kerja Wanita di PT. Indonesia: Akar Wangi Gianyar. Poltekkes Denpasar, Denpasar; 2019.

Bourassa MW, Osendarp SJ, Adu‐Afarwuah S, Ahmed S, Ajello C, Bergeron G, et al. Review of the evidence regarding the use of antenatal multiple micronutrient supplementation in low‐and middle‐income countries. Ann N Y Acad Sci 2019;1444(1):6. https://doi.org/10.1111/nyas.14121 PMid:31134643 DOI: https://doi.org/10.1111/nyas.14121

Keats EC, Haider BA, Tam E, Bhutta ZA. Multiple‐micronutrient supplementation for women during pregnancy. Cochrane Database Syst Rev 2019;3(3):CD004905. https://doi.org/10.1002/14651858.CD004905.pub6 PMid:30873598 DOI: https://doi.org/10.1002/14651858.CD004905.pub6

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Published

2022-01-01

How to Cite

1.
Sakung J, Tosae D, Gunarmi G, Arundhana AI. Differences in Hemoglobin Levels in Pregnant Women through Multi-Micronutrient Supplements and Iron Tablets. Open Access Maced J Med Sci [Internet]. 2022 Jan. 1 [cited 2024 Apr. 26];10(B):1-5. Available from: https://oamjms.eu/index.php/mjms/article/view/7794

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Gynecology and Obstetrics

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