Serum Level of the Adipokine “Vaspin” in Relation to Metabolic Parameters: Short – Term Effect of Specific Dietary Therapy

Authors

  • Maha I. A. Moaty Department of Nutrition and Food Science, National Research Center, Cairo
  • Salwa M. El Shebini Department of Nutrition and Food Science, National Research Center, Cairo
  • Nihad H. Ahmed Department of Nutrition and Food Science, National Research Center, Cairo
  • Ahmed M.S. Hussein Food Technology Department, National Research Center, Cairo
  • Magda S. Mohamed Department of Nutrition and Food Science, National Research Center, Cairo
  • Salwa T. Tapozada Department of Nutrition and Food Science, National Research Center, Cairo
  • Laila M. Hanna Department of Nutrition and Food Science, National Research Center, Cairo

DOI:

https://doi.org/10.3889/oamjms.2014.029

Keywords:

Metabolic syndrome, vaspin, dietary therapy, doum (Hyphaene Thebaica), whole wheat.

Abstract

AIM: To investigate the association between the circulating vaspin concentration and both of glucose homeostasis and insulin resistance in metabolic syndrome (MetS) patients, and also to evaluate the metabolic impact of two different dietary therapies on such conditions.

MATERIALS AND METHODS:  Fifty eight obese female volunteers suffering from MetS, followed a specially designed dietary therapy consists of a low caloric balanced diet, accompanied by either 30% doum biscuits (group A), or whole wheat biscuits (group B) for four weeks (phase 1). During the next four weeks, they were continued on the hypocaloric diet alone (phase 2).

RESULTS: The health effects of two dietary therapies were more prominent in improving the biochemical markers of the MetS than in the body weight reduction. The lower levels of serum vaspin were significantly increased at the end of the 1st phase in both groups especially group (A). Sustained negative correlations were detected between vaspin level and both of C-peptide and insulin resistance expressed as modified homeostatic model assessment (M.HOMA).

CONCLUSION: The effect of the dietary supplements may play a role in alleviating the impact of the components of the MetS and may also sustain the level of the vaspin in the sensitization of the C-peptide in order to attain glucose homeostasis.

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Published

2014-04-08

How to Cite

1.
Moaty MIA, El Shebini SM, Ahmed NH, Hussein AM, Mohamed MS, Tapozada ST, Hanna LM. Serum Level of the Adipokine “Vaspin” in Relation to Metabolic Parameters: Short – Term Effect of Specific Dietary Therapy. Open Access Maced J Med Sci [Internet]. 2014 Apr. 8 [cited 2024 Apr. 26];2(2):185-90. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2014.029

Issue

Vol. 2 No. 2 (2014): Jun 15 (OAMJMS)

Section

A - Basic Science

License

http://creativecommons.org/licenses/by-nc/4.0

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