The The Effectiveness of Early Mobilization Time on Balance and Functional Ability after Ischemic Stroke
DOI:
https://doi.org/10.3889/oamjms.2019.269Keywords:
Early mobilization, Ischemic post-stroke, Balance, Functional abilityAbstract
BACKGROUND: Early mobilisation (EM) after-ischemic stroke is a motor learning intervention aimed to restore nerve cells and to improve balance and functional ability. Unfortunately, the study of when this intervention began has not been widely studied.
AIM: On this study was compared the effect of EM started at 24 hours and 48 hours after an ischemic stroke on balance and functional ability.
MATERIAL AND METHODS: Randomized controlled trial involving 40 patients on 2 groups meeting predefined inclusion criteria. The levels of balance were measured using the Berg Balance Scale, and the functional ability was measured using the Barthel Index, at 5th and 7th day.
RESULTS: A significant difference was observed in both balance (p = 0.038) and functional ability (p = 0.021) obtained on the 7th day of assessment between both groups. A significant difference on the 5th day was observed only in the functional ability (p = 0.002) and not in the balance (p = 0.147), between the groups.
CONCLUSION: EM started at 24 hours after the ischemic stroke has been found to have a better impact on balance and functional ability compared to that at 48 hours.
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The AVERT Trial Collaboration Group. Efficacy and safety of very early mobilization within 24 h of stroke onset (AVERT): a randomized controlled trial. Lancet. 2015; 386:5535-46.
Zhang ZG, Chopp M, Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic. Lancet Neurol. 2009; 8(5):491-500. https://doi.org/10.1016/S1474-4422(09)70061-4
Zhang P, Zhang Y, Zhang J. Early Exercise Protects against cerebral ischemic injury through inhibiting neuron apoptosis in cortex in rats. Int J Mol Sci. 2013; 14:6074-60891. https://doi.org/10.3390/ijms14036074 PMid:23502470 PMCid:PMC3634421
Li M, Peng J, Wang MD, et al. Passive movement improves the learning and memory function of rats with cerebral infarction by inhibiting neuron cell apoptosis. Mol Neurobiol. 2014; 49:216-221. https://doi.org/10.1007/s12035-013-8512-9 PMid:23925702
Morrealle M, Marchione P, Pili A, et al. Early versus delayed rehabilitation treatment in hemiplegic patients with ischemic stroke: proprioceptive or cognitive approach? Eur J Phys Rehabil Med. 2015.
Nie J, Yang X, Modulation of synaptic plasticity by exercise training as a basis for ischemic stroke rehabilitation. Cel and Mol Neurobiol. 2017; 37:5-16. https://doi.org/10.1007/s10571-016-0348-1 PMid:26910247
Rahayu UB, Wibowo S, Setyopranoto I, Development of motor learning implementation for ischemic stroke: finding consensus expert. J Med Sci. 2017; 49(4):200-216.
Hoffmann T, Glasziou P, Johnston M. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide better reporting of interventions: template for intervention description and replication (TIDieR). BMJ. 2014; 348:1687. https://doi.org/10.1136/bmj.g1687 PMid:24609605
Blum L, Korner BN. Usefulness of the berg balance scale in stroke rehabilitation: a systematic review. Phys Ther. 2008; 88:559-566. https://doi.org/10.2522/ptj.20070205 PMid:18292215
Quinn TJ, Langhorne P, Stott DJ. Barthel index for stroke trials: development, properties, and application. Stroke. 2011; 42(4):1146-1151. https://doi.org/10.1161/STROKEAHA.110.598540 PMid:21372310
Makizako H, Kobe N, Takano A, et al. Use of the berg balance scale to predict independent gait after stroke: a study of an inpatient population in japan. PM&R. 2015; 7(4):392-399. https://doi.org/10.1016/j.pmrj.2015.01.009 PMid:25633633
Hsieh Y, Wang C, Wu S, et al. Establising the minimal clinically important difference of the barthel index in stroke patients. Am Soc Neurorehabil. 2007; 21(3):233-238.
Nudo RJ. Neural bases of recovery after brain injury. J Commun Disord. 2011; 44:515-520. https://doi.org/10.1016/j.jcomdis.2011.04.004 PMid:21600588 PMCid:PMC3162095
Purves D, Augustine GJ, Fitzpatrick D, et al. Neuroscience. Sinauer Associates Massachusetts. 2004; 582.
Calford MB. Dynamic representational plasticity in sensory cortex. Neuroscience. 2002; 111(4):709-738. https://doi.org/10.1016/S0306-4522(02)00022-2
Xu T, Yu X, Ou S, Liu X, Yuan J, Chen Y. Efficacy and safety of very early mobilization in patients with acute stroke: a systematic review and meta-analysis. Scientific reports. 2017; 7(1):6550. https://doi.org/10.1038/s41598-017-06871-z PMid:28747763 PMCid:PMC5529532
Madinier A, Bertrand N, Rodier M, et al. Ipsilateral versus contralateral spontaneous post-stroke neuroplastic change: involvement of BDNF? Neuroscience. 2013: 231:169-181. https://doi.org/10.1016/j.neuroscience.2012.11.054 PMid:23219910
Bejot Y, Tessier AP, Cachia C, et al. Time-dependent contribution of non-neuronal cells to BDNF production after ischemic stroke in rats. Neurochem Int. 2018:102-111.
Chen A, Xiong L, Tong Y, et al. The neuroprotective roles of BDNF in hypoxic ischemic brain injury (Review). Biomed Rep. 2013:167-176. https://doi.org/10.3892/br.2012.48 PMid:24648914 PMCid:PMC3956206
Kim MW, Bang MS, Han TR, et al. Exercise increased BDNF and trkB in the contralateral hemisphere. Brain Res. 2005:16-21. https://doi.org/10.1016/j.brainres.2005.05.070 PMid:16054599
Matsuda F, Sakakima H, Yoshida Y, The effects of early exercise on brain damage and recovery after focal cerebral infarction in rats. Acta Physiol. 2011; 201:275-287. https://doi.org/10.1111/j.1748-1716.2010.02174.x PMCid:PMC3045711
Plow EB, Cunningham DA, Varnerin N, et al. Rethinking stimulation of the brain in stroke rehabilitation: why higher motor areas might be better alternatives for patient with greater impairments. Neuroscientist. 2015; 21(3):225-240. https://doi.org/10.1177/1073858414537381 PMid:24951091 PMCid:PMC4440790
Xing Y, Yang SD, Dong F, et al. The beneficial role of early exercise training following stroke and possible mechanisms. Life Sci. 2018:32-37. https://doi.org/10.1016/j.lfs.2018.02.018 PMid:29452165
Hosp JA, Luft AR. Cortical plasticity during motor learning and recovery after ischemic stroke. Neural Plast 2011. Hindawi Publishing Corporation.
Paillard T. Plasticity of the postural function to sport and/or motor experience. J Neurobiorev. 2017; 72:129-152. https://doi.org/10.1016/j.neubiorev.2016.11.015
Stein JH, Macho RF, Winstein JC, et al. Stroke recovery & rehabilitation. Demos Medical Publishing. New York.
McDermott A, Korner BN. Bilateral arm training in stroke engine intervention. Montreal: McGill University, 2012.
Wishart LR, Lee TD, Ezekiel HJ, et al. Application of motor learning principles: The physiotherapy client as a problem-solver. I Concepts. Physiother Can. 2000; 229-232.
Halsband U, Lange RK. Motor learning in man: a review of functional and clinical studies. J Physiol. 2006; 99:414-424. https://doi.org/10.1016/j.jphysparis.2006.03.007
Taylor JA, Ivry RB. The role of strategies in motor learning. Ann N Y Acad Sci. 2012; 1251:1-12. https://doi.org/10.1111/j.1749-6632.2011.06430.x PMid:22329960 PMCid:PMC4330992
Darekar A, McFadyen BJ, Lamontagne A, et al. Efficacy of virtual reality-based intervention on balance and mobility disorders post-stroke: a scoping review. J Neuroeng Rehabil. 2015; 12:46. https://doi.org/10.1186/s12984-015-0035-3 PMid:25957577 PMCid:PMC4425869
Lieber RL. Skeletal muscle structure, function and plasticity. The physiological basis of rehabilitation, 2nd ed. Lippincott Williams & Wilkins: London, 2002.
Lehto NK, Marley TL, Ezekiel HJ. Application of motor learning principles: the physiotherapy client as a problem-solver. IV. Future directions. Physiother Can. 2001; 109-114.
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Copyright (c) 2019 Umi Budi Rahayu, Samekto Wibowo, Ismail Setyopranoto
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