Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs

Authors

  • Denny Satria Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Jansen Silalahi Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Ginda Haro Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
  • Syafruddin Ilyas Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia
  • Poppy Anjelisa Zaitun Hasibuan Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.3889/oamjms.2019.521

Keywords:

cytoprotective, Picria fel-terrae Lour., herbs, ethylacetate

Abstract

AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria fel-terrae Lour. herbs.

METHODS: Cytoprotective activity were determined by MTT asay and flow cytometry assay on Vero cells which induced with H2O2 0.8 mM.

RESULTS: EAF at 100 µg/mL were showed highest viability (88.83 ± 2.90%) and ROS expression (66.75%) on Vero cells.

CONCLUSION: EAF of Picria fel-terrae Lour. herbs have cytoprotective activity.

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Published

2019-11-14

How to Cite

1.
Satria D, Silalahi J, Haro G, Ilyas S, Hasibuan PAZ. Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs. Open Access Maced J Med Sci [Internet]. 2019 Nov. 14 [cited 2024 Apr. 23];7(22):3865-7. Available from: https://oamjms.eu/index.php/mjms/article/view/oamjms.2019.521

Issue

Vol. 7 No. 22 (2019): Nov 30 (Herbal Medicine in Pharmaceutical and Clinical Sciences)

Section

Herbal Medicine in Pharmaceutical and Clinical Sciences

License

Copyright (c) 2019 Denny Satria, Jansen Silalahi, Ginda Haro, Syafruddin Ilyas, Poppy Anjelisa Zaitun Hasibuan (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

http://creativecommons.org/licenses/by-nc/4.0

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